Intended for scientists who have an interest in deciphering the molecular mechanisms for sequence recognition of DNA. This title covers the methods that have general applicability to small molecules as well as oligomers and proteins. It includes examples that provide general principles involved in sequence recognition.
Describes work on the modification of DNA by AT specific anticancer drugs, DNA alkylation events which involve metabolite generation, DNA sequence recognition by two selective binders,and more. This volume includes features such as: drug design and therapeutic applications; Nucleic acid-protein interactions; and more.
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