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The guest editors, Dr. William Huang and Dr. Ezequiel Becher, have assembled a state-of-the art issue devoted to Advanced and Metastatic Renal Cell Carcinoma (RCC). They have secured expert authors to contribute clinical reviews on the important topics involving treating and managing patients with RCC. Specific articles are devoted to the following topics: Imaging for Metastatic RCC; Adjuvant Therapy for Localized High Risk RCC; Current Standards for Therapeutic Sequencing for Advanced RCC; Role of Lymphadenectomy in patients with advanced RCC; Cytoreductive Nephrectomy in the Era of TKI/IO - Who, When and Why; Minimally Invasive Surgery for Patients with Locally Advanced and Metastatic Disease RCC; Evolving Role of Urologists in the Management of Advanced RCC; Neoadjuvant Therapy for Locally Advanced RCC; Epidemiology and Risk Assessment/Biomarkers for Patients with Advanced RCC; Radiation Therapy for Patients with Metastatic RCC; Evolving Role of Metastatectomy for Patients with Metastatic RCC; and Management of Non-Clear Cell Metastatic RCC. Readers will come away with the information they need to treat and manage patients and to improve outcomes.

This issue of Facial Plastic Surgery Clinics, guest edited by Dr. William H. Truswell, is devoted to Day-to-day Challenges in Facial Plastic Surgery. This issue is one of four selected each year by the series Consulting Editor, Dr. J. Regan Thomas. Articles in this issue include: Guiding the Patient on Their Journey through Facial Rejuvenation Surgery; Incorporating Nonsurgical Options and Aesthetic Services into a Facial Plastic Surgery Practice; Evaluating, Purchasing, and Incorporating High Tech Equipment into a Facial Plastic Surgery Practice; Identifying and Handling Personality Disorders when Selecting Patients for Surgery; Unhappy Patients Can Turn into Angry Patients; Balancing University Obligations and a Cosmetic Surgery Practice in a Full Time Academic Environment; The Art of Teaching, Training, and Putting the Scalpel in Residents'' Hands; Facial Plastic Surgery Journals; Recognizing, Managing, and Guiding the Patient Through Complications in Facial Plastic Surgery; Recognizing and Managing Complications in Laser Resurfacing, Chemical Peels, and Dermabrasion; Life in an Academic Practice vs. a Solo Private Practice; How to Leverage Social Media in Private Practice; The Best Business Moves You Can Use to Enhance Your Practice; Understanding and Getting Involved in the International Facial Plastic Surgery Community; and Securing Operating Room Time for Elective Cases.

This issue of Surgical Pathology Clinics, guest edited by Dr. Raul Gonzalez, will cover key topics in Gastrointestinal Pathology. This issue is one of four selected each year by our series consulting editor, Dr. Jason L. Hornick. Topics discussed in this issue will include: Grossing of Gastrointestinal Specimens: Best Practices and Current Controversies, Subspecialty Signout and Interobserver Variability in Gastrointestinal Pathology, Diagnosis and Management of Gastrointestinal Neuroendocrine Neoplasms, Daily Dilemmas in Pediatric Gastrointestinal Pathology, Upper Gastrointestinal Tract Manifestations of Inflammatory Bowel Disease, Gastric Polyps, Approaches to Biopsy and Resection Specimens of the Ampulla, Updates in Appendix Pathology, HER2 in Colorectal Carcinoma, Histology of Colorectal Carcinoma: Proven and Purported Prognostic Factors, Diagnoses and Difficulties in Mesenteric Pathology, Advances and Annoyances in Anus Pathology, among others.

The Guest Editors of this issue of Urologic Clinics of North America have put together a comprehensive collection of articles that provides the current knowledge on urologic cancer immunotherapy. Expert authors have contributed clinical review articles on the following topics: Era of personalized vaccines for GU cancers; TCR and dendritic vaccine platforms for GU cancers; Neo-adjuvant platforms for GU cancer immunotherapy; Immune-editing in Cancer: Role of tumor microenvironment and immune-suppressive pathways in localized and aggressive disease; Clinical integration of neo-adjuvant platforms for prostate cancer immunotherapy; Immunotherapy for muscle and non-muscle invasive bladder cancer: BCG and beyond; Immunotherapy for metastatic bladder cancer; Immunotherapy options for metastatic castrate-resistant prostate cancer; Role of tissue infiltrating lymphocytes: Understanding TCR; Therapeutic platforms for IPSC-derived CAR-T; Immune-suppression in prostate cancer: Underlying causes and influence on response to immunotherapy; and Racial disparity in response to immunotherapy. Urologists will come away with the most current information they need to improve outcomes in the urologic cancer patient.

This issue of Surgical Clinics of North America focuses on Wound Management and is edited by Drs. Michael D. Caldwell and Michael J. Harl. Articles will include: Complex wounds calciphylaxis and burns; What makes wounds chronic; Clinical management of difficult and slow-healing wounds; The effect of comorbidities on wound healing; Foot surgery for chronic non-healing wounds; The role of biofilms in wound healing; Plastic surgery techniques for wound coverage; Biologic and synthetic skin substitutes and ¿smart? wound dressings/coverings; Bacteria and wound healing; Use of hyperbaric oxygen therapy as an adjunct to wound healing; The history of wound healing; and more!

This issue of Otolaryngologic Clinics of North America, Guest Edited by Drs Carol Bauer, Ronna P. Hertzano, and Didier Depireux, is devoted to Tinnitus. This issue is one of six selected each year by our series Consulting Editor, Sujana S. Chandrasekhar. Articles in this important issue include: Animal Models of Tinnitus; Epidemiology and Genetics of Tinnitus; Classification of Tinnitus; Noise: Acoustic Trauma to the Inner Ear; Noise: Acoustic Trauma and Tinnitus - What Musicians Know; Noise: Acoustic Trauma and Tinnitus - The US Military Experience; Perception of and Reaction to Tinnitus: The Depression Factor; Objective Correlates of Tinnitus via Electrophysiological Correlates: DPs and ABRs; Objective Correlates of Tinnitus via Imaging; Current Medical (validated) Treatments: Cognitive Therapy; Current Medical (validated) treatments: Pharmacological Intervention; Current Medical (validated) Treatments: Medical Devices, Hearing Aids and Cochlear Implants; Alternative Treatments for Tinnitus: Alternative Medicine; Current Clinical Trials: Drug; Current Clinical Trials: Devices; Avenue for Future Treatments; and Tinnitus: An Industry Perspective.

This issue of Thoracic Surgery Clinics, guest edited by Drs. Virginia R. Litle and Robert J. Canelli, is devoted to Peri-operative Management of the Thoracic Patient. Drs. Litle and Canelli have assembled expert authors to review the following topics: Preoperative Evaluation of Patients Undergoing Thoracic Surgery; Prehab of the Thoracic Patient; Enhanced Recovery after Thoracic Surgery; Surgical Approaches for Esophagectomy: Open, Minimally Invasive, Robotic. What is the Approach Algorithm?; Intraoperative Anesthetic Management of the Thoracic Surgery Patient; Intraoperative Surgical and Anesthetic Concerns for Robotic Approach to the Thoracic Surgery Patient; Prevention of Postoperative Prolonged Air-leak after Pulmonary Resection; Intraoperative Pre-emptive Prevention of Esophagectomy Complications: Role of Feeding Tubes, Pyloric Drainage Procedures, Anastomotic Buttressing; Interventional Pulmonology: A Brave New World; Pain Management in Thoracic Surgery; Management of Complications after Lung Resections; Management of complications after esophagectomy; and more!

This issue of Facial Plastic Surgery Clinics, guest edited by Dr. Andrew A. Jacono, is devoted to Facelift Surgical Techniques. This issue is one of four selected each year by the series Consulting Editor, Dr. J. Regan Thomas. Articles in this issue include: Extended Deep Plane Facelifting, Extended SMAS Flap Rhytidectomy, Vertical Platysma Advancement Deep Plane Facelifting, Incorporating Midline Platysmaplasty with Lateral SMAS Facelifting, Subunit, Approach to Facelifting and Facial Rejuvenation, Superficial and Deep Facial Anatomy and Its Implication for Rhytidectomy Surgery, Laser Assisted Facelifting and Energy-Based Rejuvenation Techniques During Rhyrtidectomy, Incorporating Fat Grafting with Facelift Surgery, Approaches to Reducing Risk in, Rhytidectomy Surgery, Nuances in SMAS Rhytidectomy, Less Invasive SMAS Approaches in Rhytidectomy, and Local Anesthesia Facelifting.

This issue of Surgical Clinics of North America focuses on Wound Management, and is edited by Drs. Michael D. Caldwell and Michael J. Harl. Articles will include: Complex wounds, calciphylaxis and burns; What makes wounds chronic; Clinical management of difficult and slow-healing wounds; The effect of comorbidities on wound healing; Foot surgery for chronic non-healing wounds; The role of biofilms in wound healing; Plastic surgery techniques for wound coverage; Biologic and synthetic skin substitutes and "smart” wound dressings/coverings; Bacteria and wound healing; Use of hyperbaric oxygen therapy as an adjunct to wound healing; The history of wound healing; and more!

This issue of Clinics in Plastic Surgery, guest edited by Drs. Alan Matarasso and James E. Zins, is devoted to Abdominoplasty. Topics in this issue include: Lipoabdominoplasty, Progressive Tension Sutures, Abdominoplasty with Combined Surgery, Non-invasive Abdominal Surgery, Abdominoplasty in the Massive Weight Loss Patient, Lower Body Lift, Abdominal Etching, Deep Venous Thrombosis (DVT) Prophylaxis, High Definition Liposuction, and Body Q.

This issue of Neurosurgery Clinics, guest edited by Dr. R. Mark Richardson and Dr. Vasileios Kokkinos, will focus on Epilepsy Surgery: The Network Approach. This issue is one of four selected each year by our series consulting editors, Dr. Russell R. Lonser and Dr. Daniel K. Resnick. Topics discussed in this issue will include: History of the network approach in epilepsy surgery, Networks in temporal lobe epilepsy, Networks in frontal lobe epilepsy, Networks in parietal and occipital lobe epilepsy, Structures facilitating epileptogenic network formation, Extracranial interictal and ictal EEG in sEEG planning, Ictal semiology as a tool for sEEG planning, The significance of MRI lesions in sEEG planning, Functional networks in epilepsy presurgical evaluation, Automation advances in sEEG planning, Interpretation of the intracranial sEEG signal, Electrical cortical stimulation, Epileptogenic index, Modeling the epileptogenic network, Machine learning in epilepsy surgery evaluations, Neuromodulation of epilepsy networks, and Decision-making in epilepsy surgery.

This issue of Otolaryngologic Clinics of North America, Guest Edited by Drs. Ofer Jacobowitz and Maria V. Suurna, is devoted to Sleep Apnea. This issue is one of six selected each year by our series Consulting Editor, Sujana S. Chandrasekhar. Articles in this important issue include: The Goals of Sleep Apnea Treatment, Phenotypes of Obstructive Sleep Apnea, Sleep Apnea in Women, Living (or not) with Snoring, Drug-Induced Sleep Endoscopy, Sleep Studies Interpretation and Application, First in Line: The Nose, Oral Appliances, Positional Therapy for Sleep Apnea, Weight Loss - Surgical and Non-Surgical , Palatopharyngoplasty and Multilevel Surgery in the 21st Century, Getting to the Bottom of the Tongue, Implantable Neurostimulation, and Skeletal Surgery for Obstructive Sleep Apnea.

This issue of Surgical Oncology Clinics of North America, guest edited by Dr. James Howe, is devoted to Management of GI and Pancreatic Neuroendocrine Tumors. Dr. Howe has assembled expert authors to review the following topics: Introduction and History of GI and Pancreatic Neuroendocrine Tumors (GEPNETs); Surgical Management of Colorectal Neuroendocrine Tumors; Management of Metastatic GEPNETs; Pathologic considerations in GEPNETs; Medical Management of GEPNETs; Workup of GEPNETs; Peptide Radioreceptor Therapy (PRRT); Surgical Management of Small Bowel Neuroendocrine Tumors; The Role of Functional Imaging in GEPNETs; Surgical Management of Pancreatic Neuroendocrine Tumors; Surgical Management of Other Gastric and Duodenal Neuroendocrine Tumors; and more!

Together with Consulting Editor Dr. Samir Taneja, Dr. Badrinath Konety has put together a comprehensive issue that addresses the latest clinical updates in Male Infertility. Expert authors have contributed clinical review articles on the following topics: Cutting edge evaluation in male infertility; Optimal endocrine evaluation and treatment; Sperm extraction in obstructive azoospermia: What''s next; FNA vs. microTESE; ROSI (round spermatid injection); Reproductive Urology in the context of an IVF practice; Care delivery in male infertility; Qualitative research in male infertility; Male Infertility & Somatic Health; DNA fragmentation: Does testicular sperm make sense; CRISPR & Genetics of Male Infertility after whole genome sequencing; Transgenerational epigenetics: A window into paternal health influences on offspring; Spermatogonial Stem Cell Culture in oncofertility; Personalized medicine for the infertile male; and Male Infertility & The future of IVF. Readers will come away with the clinical information they need to improve outcomes in patients with infertility.

This issue of Clinics in Plastic Surgery, Guest Edited by Dr. Kevin C. Chung, is devoted to Repairing and Reconstructing the Hand and Wrist. This issue will cover both soft tissue and the bone and joint. Articles in this issue include: Approach to Fingertip Injuries; Soft Tissue Coverage of the Digits and Hands; Nerve Compression in the Upper Limb; Flexor Tendon Injuries; Tendon Transfers for Peripheral Nerve Palsies; Tendinopathy; Managing Swan-Neck and Boutonniere Deformities; The Pathogenesis and Treatment of the Stiff Digit; Nerve Tumors of the Upper Extremity; Managing Mutilating Hand Injuries; Efficiency in Digital and Hand Replantation; Hand Infections; Management of Extensor Tendon Injuries After the Flexor Tendon; Thumb Basal Joint Arthritis; Principles of Phalangeal and Metacarpal Fracture Treatment; Pediatric Hand and Wrist Fractures; Injuries Around the Proximal Interphalangeal Joint; Treatment of Carpal and Distal Radioulnar Joint Instability; Common Carpal Bone Fractures; Joint Fusion and Arthroplasty in the Hand; and Treatment of Common Congenital Hand Conditions.

This issue of Surgical Pathology Clinics will cover Current Trends in Neuropathology. Curated by Dr. David M. Meredith, this issue will explore topics in the field that are relevant for practicing clinicians. This issue is one of four selected each year by the series Consulting Editor, Jason L. Hornick. The volume will include articles on: Diversity in IDH-wildtype adult gliomas, pediatric gliomas, glioneuronal tumors, embryonal tumors, Molecular advances in tumors of the meninges, pituitary tumors, molecular diagnostics of CNS hematologic malignancies, Infectious diseases of the CNS, Iatrogenic neuropathology of systemic therapies, the future of neuropathology, the potential of digital image analysis and deep learning for CNS tumor diagnosis, and comparative evaluation of molecular and cytogenetic assays.

This issue of Clinics in Plastic Surgery, guest edited by Drs. Michael W. Neumeister and Reuben A. Bueno Jr., is devoted to Pain Management in Plastic Surgery. Articles in this important issue include: Pain Pathways and Management in Plastic Surgery; The Opioid Epidemic; Principles of Pain Management in Plastic Surgery; Epidemiology and Treatment of Chronic Generalized Musculoskeletal Pain; Pediatric Pain Management in Plastic Surgery; Enhanced Recovery After Surgery (ERAS); Imaging of Damaged Nerves; Ischemic Pain; Nerve Entrapments; Neuromas; Targeted Muscle Reinnervation; Migraine Surgery; Complex Regional Pain Syndrome; Regenerative Peripheral Nerve Interfaces; and Postoperative Pain Management in Hand and Upper Extremity Surgeries.

This issue of Otolaryngologic Clinics, guest edited by Drs. Anthony Brissett, Lisa Ishii, and Kofi Boahene, is devoted to Ethnically Sensitive Rhinoplasty. Articles in this issue include: The Changing Face of Beauty; A Global Assessment of Facial Beauty; Concepts of Facial Aesthetics When Considering Ethnic Rhinoplasty; How You See Yourself: Cultural Considerations and Self Image for Rhinoplasty Patients of Ethnic Descent; Cultural Preservation: An Ethnically Sensitive Approach to Rhinoplasty Surgery; Dorsal Modifications and Management of the Nasal Pyramid in Patients of African Descent; Management of the Nasal Tip, Nasal Base and Soft Tissue Envelope in Patients of African Descent; Endonasal Approach to the Caucasian Nose; Open Structure Approach to the Caucasian Nose; Use of Nasal Implants and Dorsal Modification When Treating the Asian Nose; Management of the Mestizo Nose; and Surgical Considerations in Patients of Middle Eastern Descent.

This issue of Clinics in Plastic Surgery, guest edited by Dr. Lee L.Q. Pu, is devoted to Fat Grafting to the Face for Rejuvenation, Contouring, or Regenerative Surgery. This issue will include an overview of current concepts and techniques of facial fat grafting, discuss personal approaches from the experts in fat grafting for facial rejuvenation, and show techniques for fat grafting for facial rejuvenation with nanofat grafts, cryopreserved fat grafts, and SVF-gel. Articles will further discuss fat grafting for facial contouring of the temporal region and midface, nose and chin, and unilateral face with SVF. Pan-facial fat injection approach to facial contouring in young Asian patients and fat grafting for the treatment of facial burns and burn scars, facial scleroderma, facial scars, and secondary facial deformity will also be discussed.

This issue of Otolaryngologic Clinics, guest edited by Drs. Michael Ruckenstein and James G. Naples, is devoted to Cranial Nerve Stimulation in Otolaryngology. Articles in this issue include: History of Cranial Nerurostimulation; Social and Ethical Considerations in Cranial Nerve Implants; Concepts in Neural Stimulation; Central Effects of Cranial Nerve Stimulation; Special Considerations in Patients with Cranial Nerve Implants; CN I- Olfactory Nerve Stimulator; Cochlear Nerve: Cochlear Implant; Cochlear Nerve: Auditory Brainstem Implant; Vestibular Nerve: Vestibular Implant; CN X- Vagal Nerve Stimulator; CN X- Recurrent Laryngeal Nerve Stimulator; CN XII- Hypoglossal Nerve Stimulator; and The Future of Cranial Nerve Stimulation.

This issue of Neurosurgery Clinics, guest edited by Dr. Nathaniel P. Brooks and Dr. Michael Y. Wang, is devoted to New Technologies in Spine Surgery. Articles in this issue include: Endoscopic Lumbar Discectomy, Endoscopic Cervical Foraminotomy, Endoscopic Lumbar Interbody Fusion, Endoscopic Lumbar Decompression, Lateral Lumbar Interbody Fusion, Retropleural Thoracic Approach, Novel Intervertebral Technologies, Surface Technologies for Fusion, Cell derived/Stem Cell Technologies for Fusion, Disk Replacement, Enhanced Recovery in Spine Surgery/Perioperative pain management, Imaging Technologies, Robotic Instrumentation Placement, Minimally Invasive Deformity Advances, Tissue Engineering/Regenerative Treatments, Minimally Invasive Tumor Ablation, and more.

This issue of Surgical Clinics of North America focuses on Robotic Surgery, and is edited by Dr. Julio Teixeira. Articles will include: History of Computer-assisted Surgery; Robotic Cardiac Surgery; Robotic Thoracic Surgery; Robotic Foregut Surgery; Robotic Liver Resection; Robotic Cholecystectomy; Robotic Pancreatic and Solid Surgery; Robotic Colorectal Surgery; Robotic Urology Surgery; Robotic Vental Hernia Surgery; Robotic Inguinal Hernia Surgery; Robotic Bariatric Surgery; Robotic Pediatric Surgery; Robotic Gynecological Surgery; Complications of Robotic Surgery; and more!

This issue of Surgical Oncology Clinics of North America, guest edited by Dr. James Howe, is devoted to Management of GI and Pancreatic Neuroendocrine Tumors. Dr. Howe has assembled expert authors to review the following topics: Introduction and History of GI and Pancreatic Neuroendocrine Tumors (GEPNETs); Surgical Management of Colorectal Neuroendocrine Tumors; Management of Metastatic GEPNETs; Pathologic considerations in GEPNETs; Medical Management of GEPNETs; Workup of GEPNETs; Peptide Radioreceptor Therapy (PRRT); Surgical Management of Small Bowel Neuroendocrine Tumors; The Role of Functional Imaging in GEPNETs; Surgical Management of Pancreatic Neuroendocrine Tumors; Surgical Management of Other Gastric and Duodenal Neuroendocrine Tumors; and more!

This issue of Surgical Oncology Clinics of North America, guest edited by Drs. Vijay Khatri and Nicholas J. Petrelli, is devoted to Precision Medicine in Surgical Oncology. Drs. Khatri and Petrelli have assembled expert authors to review the following topics: Gene Expression Profiling in Melanoma; Precision Medicine in Lung Cancer; Precision Medicine in Colon Cancer; Immunotherapy in the Treatment of Melanoma; Genomics and History of Precision Medicine; Cancer Genomics and Precision Medicine in 21st Century; Precision Medicine in Breast Cancer; Precision Medicine in Pediatrics; Establishing a Precision Cancer Medicine Program; much more!

This issue of Facial Plastic Surgery Clinics, guest edited by Drs. Lisa E. Ishii and Linda N. Lee, is devoted to Techniques for Hair Restoration. Articles in this issue include: Androgenetic Alopecia: Pathophysiology and medical therapy; Follicular Unit Transplantation; Follicular Unit Extraction; Hair Transplantation for Scarring Alopecia; Facial Hair Transplantation; Platelet Rich Plasma/Stem Cells and Hair Transplantation; Robotic Hair Transplantation; Surgical Hairline Advancement; Hair Transplantation in Women; Complications with Hair Transplantation; and The Role for Topical Hair Growth Medications.

This issue of Thoracic Surgery Clinics, guest edited by Drs. Vincenzo Ambrogi and Tommaso Mineo, is devoted to Nonintubated Thoracic Surgery. Drs. Ambrogi and Mineo have assembled expert authors to review the following topics: Technical issues and patient safety in nonintubated thoracic anesthesia; Management of primary and secondary pneumothorax in nonintubated VATS; Treatment of pleural effusions with nonintubated VATS; Nonintubated VATS for chest infections; Nonintubated VATS lung biopsy for interstitial lung disease; Nonintubated VATS wedge resection of peripheral early lung cancer; Anatomical segmentectomy in nonintubated VATS; VATS lobectomy for lung cancer in nonintubated anesthesia; Nonintubated VATS tracheal and bronchial sleeve resection for lung cancer; Nonintubated tracheal surgery; Management of intraoperative crisis during nonintubated thoracic surgery; Team training for nonintubated thoracic surgery; and more!

This issue of Facial Plastic Surgery Clinics, Guest Edited by Dr.  Richard D. Gentile, explores today''s facial skin rejuvenation technology. Articles in this issue include: Microneedling Options for Skin Rejuvenation Including Non-Temperature Controlled Fractional Microneedle Radiofrequency Treatment; Skin Rejuvenation by Temperature Controlled Bi-Polar Fractional Microneedle Radiofrequency Treatment; New Developments for Fractional CO2 Resurfacing for Skin Rejuvenation and Scar Reduction; Broad Band Light and Skin Rejuvenation; Non-Ablative and Hybrid Fractional Laser Skin Rejuvenation; Chemexfoliation Through the Ages; Prescription Skin Care Products and Skin Rejuvenation; Plasma Energy Skin Rejuvenation; A Pulsed Technique for Helium Plasma Energy Skin Resurfacing; PICO Pulsed Lasers and Skin Rejuvenation; New Frontiers in Skin Rejuvenation Including Biologics; Pre- and Post-Operative Care for Interventional Skin Rejuvenation; Easy PRF for Post Resurfacing and Microneedle Therapy; and Photodynamic Therapy.

This issue of Surgical Clinics of North America focuses on Contemporary Melanoma Management: A Surgical Perspective, and is edited by Dr. Rohit Sharma. Articles will include: Melanoma etiology and risk factors; Genetic, inherited and familial melanoma; Staging melanoma: What''s old and new; Surgical management of primary cutaneous melanoma; Surgical management of regional lymph nodes in melanoma; Non-surgical management of regional lymph nodes in melanoma; Principles of immunotherapy in melanoma; Principles of targeted therapy in melanoma; Role of radiation in the era of effective systemic therapy for melanoma; Melanoma of unusual sites; Ongoing clinical trials in melanoma; Role of surgery for metastatic melanoma; Surgical considerations and systemic therapy of melanoma; Management of loco regionally advanced melanoma; Pathology of melanoma; and more!

This issue of Neurosurgery Clinics, guest edited by Dr. Mark H. Bilsky, will cover key topics in Spinal Oncology. This issue is one of four selected each year by our series consulting editors, Dr. Russell R. Lonser and Dr. Daniel K. Resnick. Topics discussed in this issue will include: Radiation Strategies for Chordoma, New Prospects for Molecular Targets in Chordoma, Surgical Strategies for Chordoma, State of the Art Treatment for Giant Cell Tumors, NOMS and Other Decision Frameworks for Metastatic Disease, Evolving Role of SBRT in Spine Metastases, Hybrid Therapy for Metastatic Disease, Interventional Hybrid Therapy for Metastatic Disease LITT and SBRT, MIS Strategies Changing the Treatment of Spine Tumors, Intradural Tumors, SBRT for Benign Spine Tumors, and Evolving Diagnostic Treatment Paradigms for Spine and Peripheral Nerve Manifestations of NF, among others.

This issue of Otolaryngologic Clinics, Guest Edited by Drs. Adam I. Levine, Samuel Demaria Jr., and Satish Govindaraj, focuses on Anesthesia in Otolaryngology. Articles in this issue include: Perioperative Guidelines in Anesthesia; Simulation and Education in Anesthesia; Patient Safety in Anesthesia; Anesthesia and Head and Neck Trauma; Anesthesia in Diagnostic and Therapeutic Pediatric Bronchoscopy; Anesthesia in Diagnostic and Therapeutic Adult Bronchoscopy; Regional Anesthesia and Acute Pain Management; Anesthesia and Chronic Pain Management; Anesthesia and Enhanced Recovery After Head and Neck Surgery; The Difficult Airway and Anesthesia; Anesthesia and Management of the Narrow Airway; Neuro-otology and Anesthesia; Anesthesia in Critical and Postoperative Care Management; and Anesthesia for Ambulatory and Office-based ENT Surgery.