Böcker i Wiley Series on Mass Spectrometry-serien

A concise and authoritative overview of mass spectrometry instrumentation, techniques, and applications in a very readable, user-friendly format filled with chapter summaries, exercises and answers, and references to useful outside resources. * Includes numerous exercises in every chapter, with the answers at the back of the book.

Principles of Mass Spectrometry Applied to Biomolecules teaches readers how to use what they know about Mass Spectrometry's advantages and limitations to develop novel ways of using the technique for the analysis of proteins and other biomolecules.

The last few years have seen an unprecedented drive toward the application of proteomics to resolving challenging biomedical and biochemical tasks. Separation techniques combined with modern mass spectrometry are playing a central role in this drive. This book discusses the increasingly important role of mass spectrometry in proteomic research, and emphasizes recent advances in the existing technology and describes the advantages and pitfalls as well.* Provides a scientifically valid method for analyzing the approximatey 500,000 proteins that are encoded in the human genome* Explains the hows and whys of using mass spectrometry in proteomic analysis* Brings together the latest approaches combining separation techniques and mass spectrometry and their application in proteome analysis* Comments on future challenges and how they may be addressed* Includes sections on troubleshooting

This volume describes the complete process of analyzing protein sequences by mass spectrometry including sample preparation, analysis, and data interpretation at a practical level. It provides sufficient experimental detail to carry out the experiments and consistently achieve good results.

In the arena of new drug development, the rate of sample generation far exceeds the rate of sample analysis. LC/MS is an analytical tool that helps the researcher select the most promising sample for scrutiny, accelerating the discovery of new drugs. This book is the first to describe in detail the procedures and benefits of LC/MS applications.