AAA's... Quinolones and Fluoroquinolones: Man-made antibiotics... This book is designed to provide a detailed account on quinolones and fluoroquinolones. It is based on chemical and pharmacological principles which are necessary to understand synthesis, structure-activity relationships, and molecular mechanisms of drug action making it easy to read and understand for use by both undergraduate students of pharmacy and medicine, and postgraduate students of medicinalchemistry and pharmacology. Features at a glance: - Introduction to quinolone antibiotics - Classification - Structural developments, SAR and QSAR - Molecular mechanism of action - Antimicrobial spectrum & bacterial resistance - Synthesis of some important quinolones - Therapeutic uses.
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