Böcker av Howard Markel

James Watson and Francis Crick's 1953 discovery of the double helix structure of DNA is the foundation of virtually every advance in our modern understanding of genetics and molecular biology. But how did Watson and Crick do it-and why were they the ones who succeeded?In truth, the discovery of DNA's structure is the story of five towering minds in pursuit of the advancement of science, and for almost all of them, the prospect of fame and immortality: Watson, Crick, Rosalind Franklin, Maurice Wilkins, and Linus Pauling. Each was fascinating and brilliant, with strong personalities that often clashed. Howard Markel skillfully re-creates the intense intellectual journey, and fraught personal relationships, that ultimately led to a spectacular breakthrough. But it is Rosalind Franklin-fiercely determined, relentless, and an outsider at Cambridge and the University of London in the 1950s, as the lone Jewish woman among young male scientists-who becomes a focal point for Markel.The Secret of Life is a story of genius and perseverance, but also a saga of cronyism, misogyny, anti-Semitism, and misconduct. Drawing on voluminous archival research, including interviews with James Watson and with Franklin's sister, Jenifer Glynn, Markel provides a fascinating look at how science is done, how reputations are undone, and how history is written, and revised.A vibrant evocation of Cambridge in the 1950s, Markel also provides colorful depictions of Watson and Crick-their competitiveness, idiosyncrasies, and youthful immaturity-and compelling portraits of Wilkins, Pauling, and most cogently, Rosalind Franklin. The Secret of Life is a lively and sweeping narrative of this landmark discovery, one that finally gives the woman at the center of this drama her due.

The struggle against deadly microbes is endless. Diseases that have plagued human beings since ancient times still exist, new maladies like SARS make their way into the headlines, we are faced with vaccine shortages, and the threat of germ warfare has reemerged as a worldwide threat.In this riveting account, medical historian Howard Markel takes an eye-opening look at the fragility of the American public health system. He tells the distinctive stories of six epidemics–tuberculosis, bubonic plague, trachoma, typhus, cholera, and AIDS–to show how how our chief defense against diseases from other countries has been to attempt to deny entry to carriers. He explains why this approach never worked, and makes clear that it is useless in today’s world of bustling international travel and porous borders.Illuminating our foolhardy attempts at isolation and showing that globalization renders us all potential inhabitants of the so-called Hot Zone, Markel makes a compelling case for a globally funded public health program that could stop the spread of epidemics and safeguard the health of everyone on the planet.