Böcker av Mahdi Karimi

Examines smart nanocarriers that respond to internal stimuli that are intrinsic to the target site. These stimuli are specific to the cell type, tissue or organ type, or to the disease state. pH-responsive nanostructures can be used for cargo release in acidic endosomal compartments, in the lower pH of tumors, and for specific oral delivery either to the stomach or intestine.

The concept of smart drug delivery vehicles involves designing and preparing a nanostructure (or microstructure) that can be loaded with a cargo, this can be a therapeutic drug, a contrast agent for imaging, or a nucleic acid for gene therapy. This volume covers smart nanocarriers that respond to externally applied stimuli that usually involve application of physical energy.

The concept of drug targeting as a magic bullet has led to research in chemical modification to design and optimize the binding to targeted receptors. This book covers advances based on different drug delivery systems: polymeric and hyper branched nanomaterials, carbon-based nanomaterials, nature-inspired nanomaterials, and pathogen-based carriers.