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Natural Products and their Bioactives in Antidiabetic Drug DiscoveryEnables researchers to effectively understand and use bioactive compounds to target, prevent, and manage diabetesNatural Products and Their Bioactives in Antidiabetic Drug Discovery provides readers with an overview of recent research in new drug discovery against diabetic complications based on bioactives from NPs, bridging the gap between the public research institutes and private companies working to find drugs to treat diabetes. To aid in reader comprehension, the text includes case studies and illustrated examples in relevant chapters.Part one presents chapters on fundamental concepts of diabetes mellitus (DM) and recent drug discovery progress along with the various druggable targets and challenges. Part two covers bioactive compounds targeting Type-1 Diabetes. Part three focuses on Type-2 Diabetes. In Part four, the contributors address gestational DM prevention and management with natural compounds.Written by a global team of experts in the field, Natural Products and their Bioactives in Antidiabetic Drug Discovery covers sample topics such as:* Obesity risk factor in patients with T1DM and possible role of nutritional therapy in its management* Use of natural non-insulin drugs as a novel approach to enhance therapeutic outcomes against T1DM* Effectiveness of functional foods in intervening the diabetic complications and realistic results in clinical trials* Implementation of nanotechnology in improving the bioavailability and reducing the threshold dose of bioactive compounds* Various antidiabetic mechanisms of action of different polyphenols and immunomodulatory role of NPs bioactives relevance in T1DM therapy* Effects of natural products on genetics of gestational diabetesWith comprehensive coverage of recent research in new drug discovery against diabetic complications based on bioactives from NPs, Natural Products and Their Bioactives in Antidiabetic Drug Discovery is an essential resource for researchers and professionals involved in drug discovery and development, health care, medicinal chemistry, phytochemistry, plant science, and toxicology.

This book presents an extensive discussion on fundamental chemistry, classifications, structure, unique properties, and applications of various 2D nanomaterials. The advent of graphene in 2004 has brought tremendous attention to two-dimensional (2D) nanomaterials. Lately, this has prompted researchers to explore new 2D nanomaterials for cutting-edge research in diverse fields. Polymer nanocomposites (PNCs) represent a fascinating group of novel materials that exhibit intriguing properties. The unique combination of polymer and nanomaterial not only overcomes the limitations of polymer matrices, but also changes their structural, morphological, and physicochemical properties thereby broadening their application potential. The book, comprising 22 chapters, provides a unique and detailed study of the process involved in the synthesis of 2D nanomaterials, modification strategies of 2D nanomaterials, and numerous applications of 2D nanomaterials-based polymer nanocomposites. The book also emphasizes the existing challenges in the functionalization and exfoliation of 2D nanomaterials as well as the chemical, structural, electrical, thermal, mechanical, and biological properties of 2D nanomaterials-based polymer nanocomposites. The key features of this book are: Provides fundamental information and a clear understanding of synthesis, processing methods, structure and physicochemical properties of 2D materials-based polymer nanocomposites; Presents a comprehensive review of several recent accomplishments and key scientific and technological challenges in developing 2D materials-based polymer nanocomposites; Explores various processing and fabrication methods and emerging applications of 2D materials-based polymer nanocomposites. Audience Engineers and polymer scientists in the electrical, coatings, and biomedical industries will find this book very useful. Advanced students in materials science and polymer science will find it a fount of information.