Böcker av SC Sahu

Overview of current research and technologies in nanomaterial science as applied to omics science at the single cell levelGenomic and Epigenomic Effects of Environmental Engineered Nanomaterials is a comprehensive and authoritative compilation of the genetic processes and instructions that specifically direct individual genes to turn on or off, focusing on the developing technologies of engineering nanomaterials and their role in cell engineering which have become important research tools for pharmaceutical, biological, medical, and toxicological studies.Combining state-of-the art information on the impact of engineered nanomaterials in genomics and epigenomics, from a range of internationally recognized investigators from around the world, this edited volume offers unique insights into the current trends and future directions of research in this scientific field.Genomic and Epigenomic Effects of Environmental Engineered Nanomaterials includes detailed information on sample topics such as:* Impact of engineered nanomaterials in genomics and epigenomics, including adverse impact on glucose energy metabolism* Toxicogenomics, toxicoepigenomics, genotoxicity and epigenotoxicity, and mechanisms of toxicogenomics and toxicoepigenomics* Adverse effects of engineered nanomaterials on human environment and metabolomics pathways leading to ecological toxicity* Meta-analysis methods to identify genomic toxicity mechanisms of engineered nanomaterials and biological effects of engineered nanomaterial exposure* Artificial intelligence and machine learning of single-cell transcriptomics of engineered nanoparticles and trends in plant nano-interaction to mitigate abiotic stressesThis comprehensive work is a valuable and excellent source of authoritative and up-to-date information for advanced students and researchers, toxicologists, the drug industry, risk assessors and regulators in academia, industry, and government, as well as for clinical scientists working in hospital and clinical environments.

Genomic and Epigenomic Biomarkers of Toxicology and DiseaseThe latest developments in biomarker research applicable to toxicology and medicineResearch on genomic and epigenomic biomarkers is developing rapidly with cutting-edge studies scattered throughout the academic literature, making the status of ongoing scientific activity in this area difficult to ascertain.Genomic and Epigenomic Biomarkers of Toxicology and Disease: Clinical and Therapeutic Actions delivers a comprehensive and authoritative compilation of up-to-date developments in the application of genomic and epigenomic biomarkers to toxicology, disease prevention, cancer detection, therapeutics, gene therapy, and other areas. With contributions from a collection of internationally recognized investigators, this edited volume offers unique insights into current trends and future directions of research in the discussed areas.Combining state-of-the-art information on genomic and epigenomic biomarkers from a range of specialists from around the world, this monograph includes:* A thorough introduction to microRNAs as non-invasive biomarkers of toxicity and chemical hazard* Comprehensive explorations of extracellular vesicle-associated miRNAs as toxic biomarkers, as well as transcriptomic applications in toxicology and medicine* Practical discussions of circulating miRNAs as biomarkers of metal exposure, as well as microRNAs biomarkers of malignant mesothelioma* In-depth examinations of the role of noncoding RNAs in innate immune responses perturbed by environmental arsenic with a focus on microRNAsPerfect for researchers, toxicologists, risk assessors, and regulators, Genomic and Epigenomic Biomarkers of Toxicology and Disease: Clinical and Therapeutic Actions will also earn a place in the libraries of graduate students with an interest in biomarkers, toxicology, agriculture, or the environment.

A comprehensive and authoritative compilation of up-to-date developments in stem cell research and its use in toxicology and medicine* Presented by internationally recognized investigators in this exciting field of scientific research* Provides an insight into the current trends and future directions of research in this rapidly developing new field* A valuable and excellent source of authoritative and up-to-date information for researchers, toxicologists, drug industry, risk assessors and regulators in academia, industry and government

This book describes cutting-edge molecular technologies to unravel epigenetic changes, the use of in vivo and in vitro models, as well as the potential use of toxicological epigenetics in regulatory environments.

Frontiers in Toxicology is the essential tool for toxicologists and pharmacologists working in academia, industry and regulatory bodies looking to stay at the forefront of three of the most important and upcoming areas of toxicology: toxicogenomics, hepatotoxicity and nanotoxicity.

Nanomaterials - substances smaller than 100 nanometers in size - have been added in recent years to an increasing numbers of consumer products used in day-to-day life; in food packaging, medical devices, pharmaceuticals, cosmetics, odor-resistant textiles and household appliances.

This book addresses all the current, up-to-date developments in this scientific discipline. Liver is the chief metabolizing site in the body, and thus, it is a major target organ for drug and chemical toxicity. Therefore, hepatotoxicity is an important endpoint in the safety evaluation of drugs and chemicals.