Böcker av Sudip Mukherjee

This book presents the recent developments in immunomodulatory biomaterials for cell-based therapies in various diseases, including diabetes, cancer, cardiovascular disease, and bone regeneration. The authors first cover the fundamentals of conventional immunology and immunomodulation, before focusing on the history, advantages, and challenges of cell therapies. Biological cell therapy has gained immense attention for various diseases due to unique advantages it has over chemical drugs regarding cost, ease of production, toxicity, and therapeutic efficacy. However, these cell-based therapies need an inert delivery system that can locally deliver cells and minimally elicit foreign body response. The book discusses the foreign body response to the immunomodulatory biomaterials as well as the current and future strategies for potential mitigation of considerable immune responses toward immunomodulatory biomaterials and devices.

This book highlights recent developments of organic and inorganic nanomedicine that play a major role in anti-angiogenic cancer therapy.  In addition, the authors present examples of nanomedicine based anti-angiogenic agents and their applications in cancer therapy.  Angiogenesis is a pathophysiological phenomenon that modulates cell proliferation and cell migration and plays important roles in cancer.  Anti-angiogenic nanotherapies have gained immense attention in recent times as alternative cost-effective therapies that opened a new dimension in cancer theranostics.  Further the challenges of the anti-angiogenic nanotherapies and possible future perspective are detailed.