Böcker av Toonika Rinken

Nowadays, the implementation of novel technological platforms in biosensor-based developments is primarily directed to the miniaturization of analytical systems and lowering the limits of detection. Rapid scientific and technological progress enables the application of biosensors for the online detection of minute concentrations of different chemical compounds in a wide selection of matrixes and monitoring extremely low levels of biomarkers even in living organisms and individual cells. This book, including 16 chapters, characterizes the present state of the art and prospective options for micro and nanoscale activities in biosensors construction and applications.

Rapid multiplex detection of pathogens in the environment and in our food is a key factor for the prevention and effective treatment of infectious diseases. Biosensing technologies combining the high selectivity of biomolecular recognition and the sensitivity of modern signal detection platforms are a prospective option for automated analyses. They allow rapid detection of single molecules as well as cellular substances. This book, including 12 chapters from 50 authors, introduces the principles of identification of specific pathogen biomarkers along with different biosensor-based technologies applied for pathogen detection.

As biosensors comprise a prospective alternative to traditional chemical analyses, enabling fast on- and in-line measurements with sufficient selectivity, the field isexpanding rapidly and is offering new ideas and developments every day. This book aims to cover the present state of the art in the biosensor technology and introduce the general aspects of biosensor- based techniques and methods. The book consists of 13 chapters by 44 authors and is divided into 3 sections, focused on bio-recognition techniques, signal transduction methods and signal analysis.

The main challenge in biosensor development is their application for various practical tasks to provide a continuous and reliable flow of information about the indicators of natural and industrial processes and the surroundings, so enabling adequate feedback and control. Biosensors can provide essential information, as the quality of life depends mainly on our knowledge about what we breathe, what we eat and how our bodies are able to metabolize the material, which we contact. This book includes 14 chapters, written by 52 authors and is focused on the applications of biosensors for monitoring the parameters of environment, the quality of food and biomarkers of health.

Biosensors are analytical devices for selective detection of an analyte or a group of analytes that combine biological material with a physicochemical detector, yielding a measurable signal. Biosensors are used in various fields of human activity, including environmental and clinical analyses, food analyses and control of industrial processes. Most efforts in biosensor studies have been focused on the fabrication of various combinations of biological components and measuring systems; less attention has been paid to the interpretation of factors, affecting the formation of biosensor output signal and the problems of biosensor calibration. So in many cases only a fraction of potentially available information is taken into consideration, making the biosensor analyses less reliable than they actually could be. The present work is an effort to solve some of the problems in biosensor signal analysis, proposing a new approach to signal modelling and calibration of biosensors, based on oxidoreductases; just to promote the application of these biosensors for on-line analyses.