Böcker utgivna av Elsevier Science Publishing Co Inc

Targeted Cancer Imaging: Design and Synthesis of Nanoplatforms based on Tumour Biology reviews and categorizes imaging and targeting approaches according to cancer type, highlighting new and safe approaches that involve membrane-coated nanoparticles, tumor cell-derived extracellular vesicles, circulating tumor cells, cell-free DNAs, and cancer stem cells, all with the goal of pointing the way to developing precise targeting and multifunctional nanotechnology-based imaging probes in the future. This book is highly multidisciplinary, bridging the knowledge gap between tumor biology, nanotechnology, and diagnostic imaging, and thus making it suitable for researchers ranging from oncology to bioengineering. Although considerable efforts have been conducted to diagnose, improve and treat cancer in the past few decades, existing therapeutic options are insufficient, as mortality and morbidity rates remain high. One of the best hopes for substantial improvement lies in early detection. Recent advances in nanotechnology are expected to increase our current understanding of tumor biology, allowing nanomaterials to be used for targeting and imaging both in vitro and in vivo experimental models.

Research Data Management and Data Literacies help researchers familiarize themselves with RDM, and with the services increasingly offered by libraries. This new volume looks at data-intensive science, or `Science 2.0¿ as it is sometimes termed in commentary, from a number of perspectives, including the tasks academic libraries need to fulfil, new services that will come online in the near future, data literacy and its relation to other literacies, research support and the need to connect researchers across the academy, and other key issues, such as `data deluge,¿ the importance of citations, metadata and data repositories. This book presents a solid resource that contextualizes RDM, including good theory and practice for researchers and professionals who find themselves tasked with managing research data.

Tensors for Data Processing: Theory, Methods and Applications presents both classical and state-of-the-art methods on tensor computation for data processing, covering computation theories, processing methods, computing and engineering applications, with an emphasis on techniques for data processing. This reference is ideal for students, researchers and industry developers who want to understand and use tensor-based data processing theories and methods. As a higher-order generalization of a matrix, tensor-based processing can avoid multi-linear data structure loss that occurs in classical matrix-based data processing methods. This move from matrix to tensors is beneficial for many diverse application areas, including signal processing, computer science, acoustics, neuroscience, communication, medical engineering, seismology, psychometric, chemometrics, biometric, quantum physics and quantum chemistry.

Approx.478 pages

The Vascular Endothelium: A Holistic Approach for Oncology provides novel and integrated knowledge on the endothelial cells as a crucial component involved in the growth of different organs in both physiological and pathological conditions. By covering diverse aspects of anatomy, embryology, molecular biology and pathology, it details the important role of the endothelium for the pathogenesis of cancer and how this knowledge can improve the outcome of cancer research.The content is split in six parts: appearance and evolution of the endothelial cell, which discusses for instance comparative anatomy of the endothelium in relation to the vascular system; endothelial cell in embryology and organogenesis, covering the interaction between endothelial and hematopoietic cells; the lymphatic system, which brings information on lymphatic endothelial cell markers and molecular regulation of lymphangiogenesis; the anatomy of the endothelium in adults, showing the differences in the mature endothelial cells through the body; the physiology of the endothelial cells, with organ specific physiological activity of the endothelium; and the endothelial cells in cancer, discussing the use of endothelium as target for treatment and current therapeutic approaches.This book is a valuable resource for cancer researchers, oncologists and other members of biomedical field who are interested to learn more about the complexity of vascular endothelium and its impact on cancer and other related diseases.

Sustainable Design for Renewable Processes: Principles and Case Studies covers the basic technologies to collect and process renewable resources and raw materials and transform them into useful products. Starting with basic principles on process analysis, integration and optimization that also addresses challenges, the book then discusses applied principles using a number of examples and case studies that cover biomass, waste, solar, water and wind as resources, along with a set of technologies including gasification, pyrolysis, hydrolysis, digestion, fermentation, solar thermal, solar photovoltaics, electrolysis, energy storage, etc. The book includes examples, exercises and models using Python, Julia, MATLAB, GAMS, EXCEL, CHEMCAD or ASPEN. This book shows students the challenges posed by renewable-based processes by presenting fundamentals, case studies and step-by-step analyses of renewable resources. Hence, this is an ideal and comprehensive reference for Masters and PhD students, engineers and designers.

Approx.10 pages

Meso-Cenozoic Brazilian Offshore Magmatism: Geochemistry, Petrology and Tectonics presents detailed studies from different points-of-view on the geological¿particularly magmatic¿evolution of the Brazilian and South Atlantic Ocean offshore areas. This comprehensive book on geological events will help readers understand the holistic evolution of the area across geographical boundaries. Each chapter consists of an introduction, regional and local geology, methods, results, discussions, conclusions and supplementary material related to the geological development in island and seamounts in the Brazilian Platform and seafloor.

Anomaly Detection and Complex Event Processing over IoT Data Streams: With Application to eHealth and Patient Data Monitoring presents advanced processing techniques for IoT data streams and the anomaly detection algorithms over them. The book brings new advances and generalized techniques for processing IoT data streams, semantic data enrichment with contextual information at Edge, Fog and Cloud as well as complex event processing in IoT applications. The book comprises fundamental models, concepts and algorithms, architectures and technological solutions as well as their application to eHealth. Case studies, such as the bio-metric signals stream processing are presented ¿the massive amount of raw ECG signals from the sensors are processed dynamically across the data pipeline and classified with modern machine learning approaches including the Hierarchical Temporal Memory and Deep Learning algorithms. The book discusses adaptive solutions to IoT stream processing that can be extended to different use cases from different fields of eHealth, to enable a complex analysis of patient data in a historical, predictive and even prescriptive application scenarios. The book ends with a discussion on ethics, emerging research trends, issues and challenges of IoT data stream processing.

Osteobiographies: The Discovery, Interpretation and Repatriation of Human Remains contextualizes repatriation, or the transfer of authority for human skeletal remains from the perspective of bioarchaelogists and evolutionary biologists. It approaches repatriation from a global perspective, touching upon the most well-known Native American Graves Protection and Repatriation Act (NAGPRA) legislation of the United States, while also covering Canada and African countries. The book focuses on the stories behind human skeletons, analyzing their biological factors to determine evolution patterns. Sections present an overview of anatomy, genomics, and stable isotopes from dietary and environmental factors, and how to identify these in skeletal remains. The book then goes on to discuss European-origin, North American, and African paleopathology, ancient DNA links, and cultural issues and implications around repatriation. It concludes with case studies to show how information from archaeologically derived skeletons is vital to understanding human evolution and provide respectful histories behind the remains.

Functional Foods and Their Implications for Health Promotion presents functional foods, from raw ingredients to the final product, providing a detailed explanation on how these foods work and an overview of their impact on health. The book presents the functions of food against disease and discusses how healthier foods can be produced. Broken into four parts, the book presents a deep dive into plant-derived functional foods, dairy foods, marine food and beverages. The book includes case studies, applications, literature reviews and coverage of recent developments.Intended for nutritionists, dieticians, food technologists, as well as students and researchers working in nutrition, dietetics, and food science, this book is sure to be a welcomed resource.