Böcker utgivna av Elsevier Science & Technology

Osteoarthritis Health Professional Training Manual addresses current gaps in knowledge and the skills and confidence that are necessary to deliver evidence-based OA care that is consistent with international guidelines and for effective translation to clinical practice for health professionals. Written for health care professionals that meet patients with osteoarthritis in the clinic, like GPs, physiotherapists, rheumatologists, orthopedic surgeons, and MDs and PTs in training, medical students and basic researchers on osteoarthritis who want an update on the clinical aspects of OA, this book addresses the urgent need to improve health professional knowledge in managing patients with osteoarthritis.

Beauty, Aging and AntiAging covers novel and updated research and treatment options regarding the effects of aging on human physiology. Beauty perception and related molecular pathways are reviewed, along with current medical and surgical approaches to aging. The first part of the book focuses on beauty, youth, aging and its effects on the human body. In the second part, various restorative treatment approaches are reviewed in detail. Particularly, invasive treatment options and molecular pathophysiology of aging are covered in this book.

The COVID-19 Response: The Vital Role of the Public Health Professional explores population health during a pandemic and how is it different than clinical medicine. Other sections cover federal, state and local responses to COVID-19, testing for COVID-19, the implementation of public health control measures, the use of public health emergency powers, health equity, the resignation and firing of public health leaders, vaccination planning, and the future of public health post COVID-19. Leaders and practitioners working in public health practice and academia, as well as students in public health undergraduate and graduate level programs will find this book extremely useful.

Cyanobacteria are ancient, primordial oxygenic phototrophs, and probably the progenitor of oxygen-evolving photosynthesis. They are a prolific source of natural products and metabolites and vitally important for environmental biology and biotechnology. Cyanobacterial Physiology presents foundational knowledge alongside the most recent advances in cyanobacterial biology. The title examines the challenges of industrial application through an understanding of the basic molecular machinery of cyanobacteria. Sixteen chapters are organized into three sections. The first part covers basic cyanobacterial biology, emphasizing environmental biology such as photosynthesis, nitrogen fixation, circadian rhythm, and programmed cell death. The second part includes the chapters that discuss cyanobacterial extremophiles, adaptations, secondary metabolites, osmoprotectants, and toxins. The third part covers aspects of cyanobacterial application that are based on environmental biology. Leading scientists contribute chapters on cyanobacteria. Cyanobacterial Physiology presents a comprehensive and vibrant solution for researchers and engineers in biotechnology interested in cyanobacteria and their applications. Topics include the cyanobacterial cell and fundamental physiological processes; the biotechnological potential of cyanobacteria with their versatile metabolism; and advanced applications of cyanobacterial products. At each stage the book is informed by basic and applied research.

Immediately Sequential Bilateral Cataract Surgery (ISBCS): Global History and Methodology is a comprehensive guide for the safe and efficient performance of ISBCS. It provides an overview of the history, recommended protocols, necessary precautions, exclusion criteria, benefits and risks associated with this procedure, organizational standards, and more. Written by the most prominent ISBCS surgeons in the world, chapters recount the arguments for and against bilateral surgery that have been made throughout the ages, up to the present, and deliver achieved and proposed resolutions to all problems discussed. Topics such as ethics and medico-legal issues surrounding ISBCS are also discussed, and a chapter on the global evolution of bilateral cataract surgery provides readers with a complete overview of the development of ISBCS practices in countries from all continents.

Practical Data Analytics for Innovation in Medicine: Building Real Predictive and Prescriptive Models in Personalized Healthcare and Medical Research Using AI, ML, and Related Technologies, Second Edition discusses the needs of healthcare and medicine in the 21st century, explaining how data analytics play an important and revolutionary role. With healthcare effectiveness and economics facing growing challenges, there is a rapidly emerging movement to fortify medical treatment and administration by tapping the predictive power of big data, such as predictive analytics, which can bolster patient care, reduce costs, and deliver greater efficiencies across a wide range of operational functions. Sections bring a historical perspective, highlight the importance of using predictive analytics to help solve health crisis such as the COVID-19 pandemic, provide access to practical step-by-step tutorials and case studies online, and use exercises based on real-world examples of successful predictive and prescriptive tools and systems. The final part of the book focuses on specific technical operations related to quality, cost-effective medical and nursing care delivery and administration brought by practical predictive analytics.

Advances in Cancer Biomarkers Research provides a thorough and detailed description of cancer biomarkers for diagnostic, prognostic and therapeutics in several cancer types. The book presents a compendium of topics related to current advanced research, along with fundamental knowledge that will help readers fully comprehend the field of cancer biomarkers. Topics discussed include such the role of genetic mechanisms, epigenetics, DNA and microRNA in different cancers, signaling pathways and exosomes. In addition, the book discusses biomarker research applied to several cancer types, such as head and neck, urological, lung, bone tumors, hematological and neurological malignancies and breast cancers.This will be a valuable resource for cancer researchers, oncologists, graduate students and members of the biomedical field who are interested in the potential of biomarkers in cancer research and treatment.

Molecular Biomarkers in Cancer Detection and Monitoring of Therapeutics: Volume Two: Diagnostic and Therapeutic Applications discusses how molecular biomarkers are used to determine predisposition, facilitate detection, improve treatment and offer prevention guidelines for different cancers. It focuses on novel diagnostic techniques based on molecular biomarkers and their impact on treatment, covering different cancer types such as tumors in the nervous system, head and neck, oral and GI tractor, lung, breast, gastric system, leukemia and urogenital tract cancers. For each type, the book discusses the best diagnostic techniques and therapeutic approaches, thus helping readers easily identify the best solution for each case. This is a valuable resource for cancer researchers, oncologists, graduate students and other members of the biomedical field who are interested in the potential of biomarkers in cancer research.

Molecular Biomarkers in Cancer Detection and Monitoring of Therapeutics, Volume One, Discovery and Technologies discusses how molecular biomarkers are used to determine predisposition, facilitate detection, improve treatment and offer prevention guidelines for different cancer types. This first volume in the series focuses on techniques and approaches recently developed to assist in the decision of which biomarker to use for specific conditions. Topics covered include circulating tumor cells and circulating tumor DNA, exomes, tumor microenvironment, gene editing, artificial intelligence and robotics. In addition, the book discusses the development and applications of organoids and precision medicine.This book will be a valuable resource for cancer researchers, oncologists, graduate students and members of the biomedical field who are interested in the potential of biomarkers in cancer research.

Natural Products in Vector-Borne Disease Management explores the potential application of natural products in vector control and disease management. The chapters discuss the global impact of specific vector-borne diseases, gaps in management, and natural products in specific stages of development - discovery, optimization, validation, and preclinical/clinical development. Toxic effects and mechanisms of action are also discussed. This book also explores how therapeutic plant derivatives can be used to combat the vectors of infection and how natural products can be used to manage and treat vector-borne diseases like malaria, leishmaniasis, dengue, and trypanosomiasis. With the inclusion of case studies on field and clinical applications and the contributions from experts in the field, Natural Products in Vector-Borne Disease Management is an essential resource to researchers, academics, and clinicians in parasitology, virology, microbiology, biotechnology, pharmacology, and pharmacognosy working in the field of vector-borne diseases.

Handbook of Epigenetics: The New Molecular and Medical Genetics, Third Edition provides a comprehensive analysis of epigenetics, from basic biology to clinical application. This new edition has been fully revised to cover the latest and evolving topics in epigenetics, with chapters updated and new chapters added on topics such as single-cell epigenetics, DNA methylation clocks in age-related diseases, transposable elements and epigenetics, X chromosome inactivation, and the epigenetics of drug addiction, among other topics. Throughout this edition, greater emphasis falls on epigenomic analyses and incorporating multi-omics approaches rather than gene-specific analyses. In addition, this edition has also been enhanced with step-by-step instructions in research methods, as well as easy-to-digest disease case studies and clinical trials that provide context and applied examples of recent advances in disease understanding and epigenetic therapeutics. These features empower researchers to reproduce the approaches and studies discussed and aid clinical translation. Live links across chapters tie in relevant external datasets and resources.

Approx.486 pages

Viral Infections and Antiviral Therapies provides comprehensive coverage of viral infections and their transmission. Coverage includes antiviral agents, therapeutics, their mechanisms and treatment strategies. The book is organized into four sections, including an introduction to antiviral therapies, viral infections and their transmission, antiviral agents and therapeutics, and a market overview and future developments. The chapters in each section of the book discuss various key topics that are contributed to by an international group of leading experts.

Variety of bacteria are present in our environment but only a few of these bacteria causes diseases in their hosts including humans. These bacteria face different stresses in the environment as well as inside the host and adapt number of strategies for their survival. In 5 parts Bacterial Survival in the Hostile Environment covers all tactics and strategies adopted by bacteria for their survival under stressed conditions and will be focused on mechanistic insights of pathogenic adaptations to host environments (acidic environment, microaerobic conditions, immune system stress, metal stress etc., modulation of host pathways by pathogens for survival, dormancy, drug tolerance and resistance, proteins for stress survival). The content also includes different adaptation mechanisms of extremophiles to extreme environment, provides a complete and globally available advance knowledge related to bacterial survival from different perspectives and reviews the knowledge gaps and future prospects in the field of microbial adaptation for sustainable development of in the field of infection biology and pharmaceutics.

Get a broad overview of the different modalities of immersive video technologies¿from omnidirectional video to light fields and volumetric videöfrom a multimedia processing perspective. From capture to representation, coding, and display, video technologies have been evolving significantly and in many different directions over the last few decades, with the ultimate goal of providing a truly immersive experience to users. After setting up a common background for these technologies, based on the plenoptic function theoretical concept, Immersive Video Technologies offers a comprehensive overview of the leading technologies enabling visual immersion, including omnidirectional (360 degrees) video, light fields, and volumetric video. Following the critical components of the typical content production and delivery pipeline, the book presents acquisition, representation, coding, rendering, and quality assessment approaches for each immersive video modality. The text also reviews current standardization efforts and explores new research directions. With this book the reader will a) gain a broad understanding of immersive video technologies that use three different modalities: omnidirectional video, light fields, and volumetric video; b) learn about the most recent scientific results in the field, including the recent learning-based methodologies; and c) understand the challenges and perspectives for immersive video technologies.

Shaping the Future of Child and Adolescent Mental Health: Towards Technological Advances and Service Innovations coincides with the 25th International Association for Child and Adolescent Psychiatry and Allied Professions (IACAPAP) Congress in Dubai from December 5¿9, 2022. There are three overarching themes of this book. Firstly, the impact of the Internet and digital technologies on the mental health and well-being of children and adolescents, including computerized therapies, and the fundamental role of technologies to advance knowledge in the field. Secondly, a theme on harnessing the expansion of knowledge on psychiatric disorders and their treatment for children and adolescents, exemplified by chapters on different kinds of adversity in child and adolescent mental health and a chapter on precision therapeutics. Given the location of the IACAPAP Congress, the third theme focuses on aspects of child and adolescent mental health in the Eastern Mediterranean Region. Chapters provide insights into a broad range of contemporary technology- and service innovation¿related topics in child and adolescent psychiatry and mental health. These include growing up in the digital age, cyberbullying, clinical applications of big data and machine learning, computerized cognitive behavioral therapy, technology- enhanced learning, lessons from COVID-19, new understanding of the consequences of psychological trauma, autoimmune encephalitis, and precision therapeutics in depression. Acknowledging the global challenge of child and adolescent psychiatry and mental health, readers will find an emphasis on contextual challenges in the field, including innovations for scaling up of mental health intervention in low- and middle-income countries, and research and training in the Eastern Mediterranean Region.

Contemporary Management of Metastatic Colorectal Cancer: A Precision Medicine Approach summarizes current knowledge and provides evidenced-based practice recommendations on how to treat patients with metastatic colorectal cancer. The book presents topics such as pre-operating imaging, the use of molecular markers in treatment decisions, neoadjuvant therapy, synchronous colorectal liver metastasis, and minimally invasive approaches. In addition, it discusses immunotherapy, targeted therapies and survivorship. This is a valuable resource for practitioners, cancer researchers, oncologists, graduate students and members of biomedical research who need to understand more about novel treatments for colorectal cancer metastasis.