Böcker utgivna av Elsevier Science & Technology

Metagenomics: Perspectives, Methods, and Applications, Second Edition provides thorough coverage of the growing field of metagenomics. Chapters from international experts examine methods for metagenomic analysis of microbiota, metagenomic computational tools, and recent metagenomic studies in various environments and clinical settings. This emphasis on applications makes the text particularly useful for applied researchers, practitioners, clinicians and students seeking to employ metagenomic approaches to advance knowledge in the biomedical and life sciences. Case-study based application chapters include topics ranging from viral metagenome profiling, metagenomics in oral disease and health, metagenomic insights into the human gut microbiome and metabolic syndromes, and more. This new edition has been fully updated to address the rapid growth and development of metagenomics applications that are discussed by experts who detail recent developments and fresh case studies. Newly added chapters instruct in methods and implications of metagenomics in areas of growing focus, such as microbiome research, clinical diagnosis, metagenomic epidemiology, wildlife conservation, zoonotic diseases and plant microbe interaction.

Genomics and the Global Bioeconomy, a new volume in the Translational and Applied Genomics series, empowers researchers, administrators, and sustainability leaders to apply genomics and novel omics technologies to advance the global bioeconomy and sustainability. Here, more than 15 international experts illustrate--with concrete examples across various industries and areas of global need--how genomics is addressing some of the most pressing global challenges of our time. Chapters offer an in-depth, case-based treatment of various topics, from genomics technologies supporting sustainability development goals to novel synthetic biology advancements improving biofuel production, conservation, sustainable food production, bioremediation, and genomic monitoring. Editors Catalina Lopez-Correa and Adrian Suarez-Gonzalez skillfully bring clarity to this diverse and increasingly impactful research, uniting various perspectives to inspire fresh innovation in driving the global bioeconomy. -- Provided by publisher.

Risk-informed Methods and Applications in Nuclear and Energy Engineering: Modelling, Experimentation, and Validation presents a comprehensive view of the latest technical approaches and experimental capabilities in nuclear energy engineering. Based on Idaho National Laboratory¿s popular summer school series, this book compiles a collection of entries on the cutting-edge research and knowledge presented by proponents and developers of current and future nuclear systems, focusing on the connection between modelling and experimental approaches. Included in this book are key topics such as probabilistic concepts for risk analysis, the survey of legacy reliability and risk analysis tools, and newly developed tools supporting dynamic probabilistic risk-assessment. This book is an insightful and inspiring compilation of work from top nuclear experts from INL. Industry professionals, researchers and academics working in nuclear engineering, safety, operations and training will gain a board picture of the current state-of-practice and be able to apply that to their own risk-assessment studies.

The behavior analytic research community emphasizes within-subject research methodologies to study relations between individual behavior and the environment. This is unique as behavior analytic practitioners can then replicate directly the research they read when determining whether a research finding applies to the clients with whom they work. Research Ethics in Behavior Analysis: From Laboratory to Clinic and Classroom is a reference guide for behavior analysts who conduct, supervise, or consume research specific to behavior analysis. This book is sequenced to follow the natural research process, beginning with an introduction to the history of research ethics that led to modern principles and values of scientific research ethics. The reader is taken through sequential steps from obtaining resources to support a research project through participant recruitment, conducting the study, communicating results, and supporting replication. Each chapter incorporates critical and under-discussed topics unique to research ethics in behavior analysis such as diversity, equity, and inclusion in the research process; balancing methodological rigor with clinical outcomes; aligning research and clinical goals; assessing generalization of research findings; the gray lines of assent and consent for intervention versus research; identifying and obtaining resources to support research; conflicts of interest; using technology and social media; and ethically handling data.

Modelling and Control Dynamics in Microgrid Systems with Renewable Energy Resources looks at complete microgrid systems integrated with renewable energy resources (RERs) such as solar, wind, biomass or fuel cells that facilitate remote applications and allow access to pollution-free energy. Designed and dedicated to providing a complete package on microgrid systems modelling and control dynamics, this book elaborates several aspects of control systems from classical approach to advanced techniques based on artificial intelligence. It captures the typical modes of operation of microgrid systems with distributed energy storage applications like battery, flywheel, electrical vehicles infrastructures that are integrated within microgrids with desired targets. More importantly, the techno-economics of these microgrid systems are well addressed to accelerate the process of achieving the SDG7 i.e., affordable and clean energy for all (E4ALL). This reference presents the latest developments including step by step modelling processes, data security and standards protocol for commissioning of microgrid projects, making this a useful tool for researchers, engineers and industrialists wanting a comprehensive reference on energy systems models.

Sustainable Development and Pathways for Food Ecosystems: Integration and Synergies is a science-based reference which focuses on several illustrated patterns that explore the roles played by the agri-food ecosystems, their functions and needs, and the importance of the interdependencies among them. This book explores the relationships and interdependencies between food ecosystems, highlighting the role each entity has in exploiting, transforming, preserving and conserving the others. It is a great resource of information on the ecosystems that surround the food supply chain and includes all processes from primary production of food through consumption.Sections cover the agricultural phase, processing and transformation, storage and consolidation, packaging, transportation and the management of waste and losses. This will be a useful reference for academicians, researchers and all the personnel involved with agri-food sector management.

Financial Trading and Investing, Third Edition provides a useful introduction to trading and market microstructure for advanced undergraduate as well as master¿s students. Without demanding a background in econometrics, the book explores alternative markets and highlights recent regulatory developments, implementations, institutions and debates. The text offers explanations of controversial trading tactics (and blunders) such as high-frequency trading, dark liquidity pools, fat fingers, insider trading and flash orders, emphasizing links between the history of financial regulation and events in financial markets. It includes coverage of valuation and hedging techniques, particularly with respect to fixed income and derivative securities. The text adds a chapter on financial utilities and institutions that provide support services to traders and updates regulatory matters. Combining theory and application, this book provides a practical beginner's introduction to today's investment tools and markets with a special emphasis on trading.

Venous Ulcers, Second Edition, provides a comprehensive synthesis of evidence-based recommendations and the highest level of expertise from a leading group of doctors, which is a fundamental constituent for the appropriate management of nonhealing venous wounds in everyday practice. This book offers a fertile environment for a complete understanding of genetics and molecular and biochemical mechanisms that lead to the development and progression of venous ulcers, which is essential for elucidating the underlying pathophysiology and can be utilized for developing novel therapies and accessing previously inaccessible areas of research. Socioeconomic impact, impact on health-related quality of life, the clinical course of the disease, and diagnostic algorithms are elaborated in detail. All currently available treatment modalities are explained in a clinically applicable approach with particular emphasis on operative technique, technical feasibility, success rates (both clinical and technical), and side effects. Lastly, this book elaborates on special diagnostic considerations and management of the most complex patients, often requiring the highest level of expertise for successful treatment.

Medicinal Chemistry of Chemotherapeutic Agents: A Comprehensive Resource of Anti-infective and Anti-cancer Drugs focuses on the basics and fundamentals of chemistry involved in chemotherapeutic agents. Each chapter comprises distinct chemical classifications that include structure and IUPAC nomenclature, synthetic schemes and routes for each drug, mechanism of the drug action, metabolic pathway and structure¿activity relationship (SAR) studies. The book covers current research focused on drug resistance and methods to overcome it, the development of newer drugs belonging to each category of the chemotherapeutic agents, molecules currently under clinical trials, and newly approved drugs, if any. This book will be a valuable resource for academics and researchers, helping them to understand the fundamentals of the medicinal chemistry of the chemotherapeutic agents.

Comprehensive Guide to Heterogeneous Networks discusses the fundamental motivations behind this cutting-edge development, along with a brief discussion on the diverse definitions of HNs. The future of heterogeneous wireless networks (HWNs) is covered, including test cases, cost configuration, economic benefits and basic challenges. Other sections cover the topology management method in context of heterogeneous sensor nodes with diverse communication and sensing range. In addition, an outline of the pros and cons of the clustering criteria in HWSNs and taxonomy are summarized and provide futuristic research directions. Final sections discuss the future evolution of HNs and their implementations in diverse applications. This is an essential reference book for advanced students on courses in wireless communications, clinical engineering and networking. It will also be of interest to researchers, network planners, technical mangers and other professionals in these fields.

Digital Therapeutics for Mental Health and Addiction: The State of the Science and Vision for the Future presents the foundations of digital therapeutics with a broad audience in mind, ranging from bioengineers and computer scientists to those in psychology, psychiatry and social work. Sections cover cutting-edge advancements in the field, offering advice on how to successfully implement digital therapeutics. Readers will find sections on evidence for direct-to-consumer standalone digital therapeutics, the efficacy of integrating digital treatments within traditional healthcare settings, and recent innovations currently transforming the field of digital therapeutics towards experiences which are more personalized, adaptable and engaging. This book gives a view on current limitations of the technology, ideas for problem-solving the challenges of designing this technology, and a perspective on future research directions. For all readers, the content on cultural, legal and ethical dimensions of digital mental health will be useful.

Febrile seizures are the most common seizures in infants and children worldwide, This fact provides strong impetus to study and understand them and their consequences, and consider their treatment. These topics were the focus of the first edition of this book. The 20 years since the publication of this first edition have witnessed an explosion of new information about febrile seizures, meriting this new edition. Key advances have been made in the genetics and neurobiological underpinnings of febrile seizures and especially the very long fever-related seizures called febrile status epilepticus. The role of neuroinflammatory factors in the emergence of these seizures and their consequences, the demonstration of unique clinical and neuroradiological aspects of febrile status epilepticus, and the prospect of predictive (bio)markers to identify and characterize cognitive and epilepsy outcomes are exciting and important. In this edition, the authors and editors tackle these developments in chapters addressing the questions of parents, physicians, allied health care professionals and basic and translational scientists.

Control of Power Electronic Converters and Systems, Volume Four covers emerging topics in the control of power electronics and converters not covered in previous volumes, including emerging power converter topologies, storage systems, battery chargers and the smart transformer. This updated edition specifically focuses on emerging power converter topologies and discusses very recent advances and topics with applications in power electronics and formidable probable dynamics. Chapters include modeling of power converters and their control, with supportive simulations and additional experimental results.Anyone looking for fundamental knowledge regarding new trends in power electronics by application, and also ready to use models and methodologies in their design, control and testing will find this the next invaluable resource in this highly regarded series.

Discoveries in Pharmacology: Volume 1: Nervous system and hormones (2nd Ed.) presents selected articles from the historic Discoveries in Pharmacology series enhanced with commentary from contemporary scholars about the reception and importance of the chapter along with an updated bibliography on the subject with contributions from a Nobel Prize winner and other pioneers in Pharmacology. The Discoveries in Pharmacology series brought acknowledged experts in their fields together to provide first-hand accounts of important pharmacological discoveries discussing the scientific background and stories behind these pivotal moments. They allow a true understanding of the means by which pharmacological discoveries are made. This volume brings forth discussions on key discoveries in psycho- and neuro-pharmacology, haemodynamics, and hormones including chapters on antipsychotic agents by Nobel winner Anders Carlsson, Willy Haefely on benzodiazepine, and butyrophenone-type neuroleptics by P. A. J. Janssen and J. P. Tollenaere. Academic and industry researchers in pharmacology and medicine, as well as advanced students in the area will find this series a useful teaching tool and launch to new discoveries. Chapters can also be used to supplement course material in pharmacology and medical courses. It will also be of interest to those who are interested in the history of medicine.

Primer on the Autonomic Nervous System, Fourth Edition provides a concise and accessible overview of autonomic neuroscience for students, scientists, and clinicians. The book's 142 chapters draw on the expertise of more than 215 basic scientists and clinicians who discuss key information on how the autonomic nervous system controls the body, particularly in response to stress. This new edition also focuses on the translational crossover between basic and clinical research. In addition to comprehensively covering all aspects of autonomic physiology and pathology, topics such as psychopharmacology decoding and modulating nerve function are also explored.

Asthma in the 21st Century: New Research Advances provides an overview on asthma, with discussions on its heterogeneity, risk factors and their interrelations, and e-health in an aging world based on current research knowledge. The book covers heterogeneity of the disease beyond severe asthma, new risk factors, new diagnoses with climate change, a focus on chemical exposures at home, e-health and links with aging, and notable advances in key areas such as diet and microbiota, the genetics of asthma, and the asthma versus COPD debate. Worldwide, the total number of asthma sufferers is estimated to be ~270 million with an additional 100 million expected to develop asthma by 2025, and asthma is the most common chronic disease among children. There are a number of clinical books available on asthma, but none with much discussion on current scientific findings and new disease understanding. Yet, the concept of asthma has evolved quickly in the past 5¿10 years, with many clinicians struggling to keep up with new scientific findings.

Computers as Components: Principles of Embedded Computing System Design, Fifth Edition continues to focus on foundational content in embedded systems technology and design while updating material throughout the book and introducing new content on machine learning and Internet-of-Things (IoT) systems.

Oil and Gas Chemistry Management Series brings an all-inclusive suite of tools to cover all the sectors of oil and gas chemicals from drilling, completion to production, processing, storage, and transportation. The third reference in the series, Recovery Improvement, delivers the critical chemical basics while also covering the latest research developments and practical solutions. Organized by the type of enhanced recovery approaches, this volume facilitates engineers to fully understand underlying theories, potential challenges, practical problems, and keys for successful deployment. In addition to the chemical, gas, and thermal methods, this reference volume also includes low-salinity (smart) water, microorganism- and nanofluid-based recovery enhancement, and chemical solutions for conformance control and water shutoff in near wellbore and deep in the reservoir. Supported by a list of contributing experts from both academia and industry, this book provides a necessary reference to bridge petroleum chemistry operations from theory into more cost-efficient and sustainable practical applications.

The Enhanced Oil Recovery Series delivers a multivolume approach that addresses the latest research on various types of EOR. The second volume in the series, Gas Injection Methods, helps engineers focus on the latest developments in one of the fastest growing areas. Different techniques are described in addition to the latest technology such as data mining and unconventional reservoirs. Supported field case studies are included to show a bridge between research and practical application, making it useful for both academics and practicing engineers. Structured to start with an introduction on various gas types and different gas injection methods, screening criteria for choosing gas injection method, and environmental issues during gas injection methods, the editors then advance on to more complex content, guiding the engineer into newer topics involving CO2 such as injection in tight oil reservoirs, shale oil reservoirs, carbonated water, data mining, and formation damage. Supported by a full spectrum of contributors, this book gives petroleum engineers and researchers the latest research developments and field applications to drive innovation for the future.

Understanding Personalization: New Aspects of Design and Consumption addresses the global phenomenon of personalization that affects many aspects of everyday life. The book identifies the dimensions of personalization and its typologies. Issues of privacy, the ethics of design, and the designer/maker¿s control versus the consumer¿s freedom are covered, along with sections on digital personalization, advances in new media technologies and software development, the way we communicate, our personal devices, and the way personal data is stored and used. Other sections cover the principles of personalization and changing patterns of consumption and development in marketing that facilitate individualized products and services. The book also assesses the convergence of both producers and consumers towards the co-creation of goods and services and the challenges surrounding personalization, customization, and bespoke marketing in the context of ownership and consumption.

Meta-Learning, or learning to learn, has become increasingly popular in recent years. Instead of building AI systems from scratch for each machine learning task, Meta-Learning constructs computational mechanisms to systematically and efficiently adapt to new tasks. The meta-learning paradigm has great potential to address deep neural networks' fundamental challenges such as intensive data requirement, computationally expensive training, and limited capacity for transfer among tasks.This book provides a concise summary of Meta-Learning theories and their diverse applications in medical imaging and health informatics. It covers the unifying theory of meta-learning and its popular variants such as model-agnostic learning, memory augmentation, prototypical networks, and learning to optimize. The book brings together thought leaders from both machine learning and health informatics fields to discuss the current state of Meta-Learning, its relevance to medical imaging and health informatics, and future directions.

Advances in Clinical Chemistry, Volume 109, the latest installment in this internationally acclaimed series, contains chapters authored by world-renowned clinical laboratory scientists, physicians and research scientists. The serial discusses the latest and most up-to-date technologies related to the field of clinical chemistry, with this new release focusing on Biomarkers of dysfunctional visceral fat, Immunoassay Design and Biotin Interference, Orexin/Hypocretin and Major Psychiatric Disorders and more. Provides the most up-to-date technologies in clinical chemistry and clinical laboratory scienceAuthored by world renowned clinical laboratory scientists, physicians and research scientists Presents the international benchmark for novel analytical approaches in the clinical laboratory