Foundations of Colorectal Cancer provides a holistic and comprehensive dive into colorectal cancer, discussing the contributions of each discipline that studies it, allowing its understanding from the most demographic and ethical facts, to the treatment process, its varieties and genetic background. Written by experts in diverse areas such as cancer research, oncology, genetics, biochemistry, psychology, social sciences, bioinformatics and palliative care, the book brings real-world experiences to help readers with any challenge they may face when dealing with patients or during their research workflow.The content is split into nine sections: Clinical manifestations and disease detection, covering primary and secondary prevention, and the role of primary care; Diagnosis and staging, discussing endoscopy, colonoscopy, molecular pathology, and anatomopathological diagnosis; Treatment, including endoscopic, surgical, radiological, and postoperative approaches; Molecular and biological mechanisms, with the role of intestinal microbiota, stem cells and signaling pathways; New diagnostic methods, encompassing biomarkers and bioinformatics tools for research; Biobanks, with an overview of their regulations and importance in the research; Epidemiological studies, focusing on incidence and mortality globally and by regions; Hereditary colorectal cancer, differentiating nonpolyposis and polyposis types; and Addressing the consequences of colorectal cancer, covering psychological effects, nutrition and ethical issues.
Prehospital Transport and Whole-body Vibration helps medical transport professionals and vehicle and equipment designers understand the concepts of human response to whole body vibration in order to shed light on the ongoing debate on the effectiveness of current immobilization systems. Written for anyone working with patients who have been medically transported, such as emergency medicine physicians, medics, ER nurses, and those researching and studying whole-body vibration (medical students, ergonomists, human factor researchers, engineers, system developers), this book takes an informative look at situations that occur in the air, on the sea and in ground medical vehicles en route to a hospital. The transport of supine humans under these conditions may lead to severe involuntary motions of body segments, which can generate discomfort, pain and secondary injuries, especially when the patient has a suspected spinal cord injury. This book will help medical transport professionals and vehicle and equipment designers understand the basic concepts of human response to whole body vibration and shed light on the ongoing debate on the effectiveness of current immobilization systems.
Spider Evolution: Genetics, Behavior, and Ecological Influences provides a thorough exploration of the evolutionary trail of arachnids, particularly spider species, from prehistoric origins to current sustainability issues. This book analyzes extinct organisms in the Arachnida class, specifically looking at their phylogenomics and molecular footprints to understand evolutionary changes in diversification in today¿s species. Sections cover spider origins and their influences on behavioral traits, physiology of sensory organs, and biomechanics, also touching on spiders as prey and predators and how their roles have changed in the 400 million years of Arachnida existence. The book then focuses upon current environmental issues facing spider species and how these have, and can, affect the evolution of these organisms. Topics include biodiversity minimization, climate change and natural disasters. This book is a much-needed resource for entomologists and arachnid- or arthropod-driven researchers. Advanced undergraduate and graduate students will also benefit from the historic review, current assessment and future predictions of spider evolution provided in this book.
A Molecular Approach to Immunogenetics, Immunogenetics: A Molecular and Clinical Overview, Volume One provides readers with an exclusive, updated overview on the scientific knowledge, achievements and findings in the field of immunogenetics. The book presents readily available, updated information on the molecular and clinical aspects of immunogenetics, from origin and development to clinical applications and future prospects. The breadth of information goes from basics to developments, clinical applications and future prospects. The book's most attractive attribute is its academic and clinical amalgamation that covers both the theoretical and practical aspects of immunogenetics. An additional feature of the book is a special chapter on viral genetics that covers COVID-19. Above all, the book contains chapters that discuss immunogenetics in relation to pharmaco-genomics and immune-toxicology.
Biosensors for Single-Cell Analysis explores a wide range of biosensor technologies and their applications in single-cell characterization and analysis. Sections cover key biophysical and chemical single-cell properties that consider proteomic, metabolic, electrical, mechanical and optical properties. Each chapter features key definitions and case studies, providing detailed guidance for researchers who want to replicate covered solutions in their work. Tutorial sections, evaluations of the current state-of-the-field and future developments are also included. Microfluidic approaches to characterization, such as microfluidic impedance flow cytometry and microfluidic flow cytometry are considered alongside more conventional approaches, such as mass spectroscopy, fluorescent and mass flow cytometry. Additionally, key types of biosensors are covered, including atomic force microscopy, micropipette aspiration, optical tweezers, microfluidic hydrodynamic stretchers, microfluidic constriction channel and microfluidic optical stretchers.
In an uncertain and complex environment, to ensure secure and stable operations of large-scale power systems is one of the biggest challenges that power engineers have to address today. Traditionally, power system operations and decision-making in controls are based on power system computations of physical models describing the behavior of power systems. Largely, physical models are constructed according to some assumptions and simplifications, and such is the case with power system models. However, the complexity of power system stability problems, along with the system's inherent uncertainties and nonlinearities, can result in models that are impractical or inaccurate. This calls for adaptive or deep-learning algorithms to significantly improve current control schemes that solve decision and control problems. Cyberphysical Infrastructures in Power Systems: Architectures and Vulnerabilities provides an extensive overview of CPS concepts and infrastructures in power systems with a focus on the current state-of-the-art research in this field. Detailed classifications are pursued highlighting existing solutions, problems, and developments in this area.
Plant Factory Basics, Applications, and Advances takes the reader from an overview of the need for and potential of plant factories with artificial lighting (PFALs) in enhancing food production and security to the latest advances and benefits of this agriculture environment. Edited by leading experts Toyoki Kozai, Genhua Niu, and Joseph Masabni, this book aims to provide a platform of PFAL technology and science, including ideas on its extensive business and social applications towards the next-generation PFALs. The book is presented in four parts: Introduction, Basics, Applications, and Advanced Research. Part 1 covers why PFALs are necessary for urban areas, how they can contribute to the United Nations' Sustainable Development Goals, and a definition of PFAL in relation to the term "indoor vertical farm." Part 2 presents SI units and radiometric, photometric, and photonmetric quantities, types, components, and performance of LED luminaires, hydroponics and aquaponics, and plant responses to the growing environment in PFALs. Part 3 describes the indexes and definition of various productivity aspects of PFAL, provides comparisons of the productivity of the past and the present operation of any given PFALs, and compares PFALs with one another from the productivity standpoint by applying the common indexes. Part 4 describes the advances in lighting and their effects on plant growth, breeding of indoor and outdoor crops, production of fruiting vegetables and head vegetables, and concluding with a focus on a human-centered perspective of urban agriculture. Providing real-world insights and experience, Plant Factory Basics, Applications, and Advances is the ideal resource for those seeking to take the next step in understanding and applying PFAL concepts.
Uses a tutorial approach to show students how to develop effective parallel programs with MPI, Pthreads, and OpenMP. This title focuses on designing, debugging and evaluating the performance of distributed and shared-memory programs. It explains how to develop parallel programs using MPI, Pthreads, and OpenMP programming models.
Natural products in the plant and animal kingdom offer a huge diversity of chemical structures that are the result of biosynthetic processes that have been modulated over the millennia through genetic effects. This book covers the synthesis or testing and recording of the medicinal properties of natural products.
Natural products in the plant and animal kingdom offer a huge diversity of chemical structures that are the result of biosynthetic processes that have been modulated over the millennia through genetic effects. This title covers the synthesis or testing and recording of the medicinal properties of natural products.
Presents the use of UV spectrophotometry for water and wastewater quality monitoring. Using practical examples, this book shows how this technique can be a source of new methods of characterization and measurement. It provides a theoretical basis for further research in the field of spectra exploitation and contains helpful practical applications.
Heat exchangers, being fundamental components of energy and process systems, are both savers and spenders of energy. This work presents the ideas and industrial concepts in compact heat exchanger technology.
Nano-Pharmacokinetics and Theranostics: Advancing Cancer Therapy addresses from a comprehensive and multidisciplinary approach the translational aspects and clinical perspectives of nano-pharmacokinetics using cancer as a model disease. Nano-pharmacokinetics is emerging as an important sub discipline of nanoscience and medical sciences because of the increasing safety issues of nanosystems on living organisms. This book reports the dynamics of nanosystems in living organisms for better understanding of nanotoxicity, pharmacology, biochemistry, physiology and medicine perspectives. It further examines current progress of state-of-the art pharmacokinetics mechanisms, which will be of great help to develop more clinical-oriented nanosystems with a wide safety margin. The book is divided into three sections: the first section focuses on the concept of pharmacokinetics with state-of-the-art Nano-Pharmacokinetics (NPK). The second section looks at the engineering of nanoparticles and pharmacokinetics clinical development. The final section focuses on Nano-Pharmacokinetics and Theranostics, elaborating the basic question of how pharmacokinetics of nanomaterials relate to their end applications such as cancer therapy. Nano-Pharmacokinetics and Theranostics: Advancing Cancer Therapy will be useful to researchers in the field of nanoparticle based targeted drug delivery including pharmaceutical scientists, material scientists, chemists, nanotechnologists, biomedical scientists, and clinicians.
Suitable for career oriented security officers in both the private and public sectors, this title offers instructors and students all learning aids, designed to reflect the trends in this industry and to support and reinforce continued professional development.
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