Nutritional Epigenomics, Second Edition, Volume Fourteen in the Translational Epigenetics series, offers a comprehensive overview of nutritional epigenomics as a mode of study, along with nutrition’s role in the epigenomic regulation of disease, health, and developmental processes. Here, an expert team of international contributors introduces readers to nutritional epigenomic regulators of gene expression, our diet’s role in epigenomic regulation of disease and disease inheritance, caloric restriction and exercise as they relate to recent epigenomic findings, and the influence of nutritional epigenomics over circadian rhythms, aging and longevity, and fetal health and development, among other processes.Disease specific chapters address metabolic disease (obesity and diabetes), cancer, and neurodegeneration, among other disorders. Diet-gut microbiome interactions in the epigenomic regulation of disease are also discussed, as is the role of micronutrients and milk miRNAs in epigenetic regulation. Finally, chapter authors examine ongoing discussions of race and ethnicity in the social-epigenomic regulation of health and disease. This new edition has been fully updated to reflect current research in the field.
Hybrid Polymeric Systems for Biomedical Applications explores the development and utilization of hybrid polymeric systems for use in a range of biomedical applications. Hybrid systems combine the specialized properties of each polymer type to produce a more targeted material which is much more tightly aligned with the intended application and outcome. This book covers a broad selection of hybrid polymeric systems as well as a variety of key biomedical applications, including tissue engineering, drug delivery, wound healing, and more.
Technical Organic and Inorganic Fibres from Natural Resources focuses on recent advances in the synthesis, processing, characterization, and application of non-textile fibers. The book provides a general introduction to the uses of natural fibers in technical textile applications while also reviewing the latest technical methods for producing these high-performance materials. As the textile industry is focused on finding alternative green fibers with the aim of providing high quality products which are fully recyclable and biodegradable, natural fibers from renewable sources play an increasingly important role in the industry due to their unique properties and functionality.
Cancer Therapy: Potential Applications of Nanotechnology provides readers with a compendium of all the latest research work in cancer therapeutics, including an emphasis on work in nanotechnology and polymeric nanoparticles. While there have been a large number of ongoing research projects and publications on the treatment of cancer, there is a limited number of books related to nanotechnology, especially those with an emphasis on polymeric nanoparticles in cancer therapy. This title enlightens researchers and students and provides exhaustive knowledge on the topics covered.
Plant Function Traits: Linking Climate and Ecosystem Functioning, part of the Plant Biology, Sustainability and Climate Change series, presents a wholistic understanding of Plant Functional Traits. As global climate change advances, natural resources are facing increasing survival challenges, hence this book directly addresses that need, exploring the morphological, physiological, and phenological properties of a plant that can be used as a proxy to understand plant environment interactions. Users will find great illustrations throughout individual chapters, along with case studies that demonstrate applications of functional traits in classifying vegetation of a region into distinct type groups as Plant Functional Types (PFTs).Additional information includes applications in the development of new generation of Dynamic Global Vegetation Model (DGVM) and an understanding of the response of vegetation to changing environments.
Complex and Composite Metal Oxides for Gas, VOC, and Humidity Sensors, Volume 2:Technology and New Trends provides an overview of the advanced nanocomposite metal oxidematerials used in sensors for environmental monitoring applications. Volume 2 discusses the state of the art in synthesis methods of innovative morphology, metal oxide hybrids, and heterostructures. It also describes the new generation of complex materials such as perovskites, spinel ferrites, and quaternary type-based gas and VOC sensors. This volume includes a brief discussion of advanced strategies for the development of futuristic sensors with properties such as room temperature operation, self-power generation, self-healability, flexibility, and wearability.
Handbook of MRI Pulse Sequences, Second Edition includes 92 self-contained sections, with each section focusing on a single subject. A new section on detailing the advanced pulse sequence techniques covers a variety of basic and advanced image reconstruction methods. The extensive topic coverage and cross-referencing makes this book ideal for beginners learning the building blocks of MRI pulse sequence design, as well as for experienced professionals who are seeking deeper knowledge of a particular technique.This book is among the most important medical imaging techniques available today. Each of these scanners is capable of running many different "pulse sequences." These sequences are governed by physics and engineering principles and implemented by software programs that control the MRI hardware.
Artificial intelligence in healthcare has become one of the best assisting techniques for clinicians in proper diagnosis and surgery. In biomedical applications, artificial intelligence algorithms are explored for bio-signals, such as electrocardiogram (ECG/EKG), electrooculogram (EOG), electromyogram (EMG), electroencephalogram (EEG), blood pressure, heart rate, and nerve conduction, and for bio-imaging modalities, such as computed tomography (CT), cone-beam computed tomography (CBCT), and MRI (magnetic resonance imaging). Advancements in artificial intelligence and big data have increased the development of innovative medical devices in healthcare applications. Advances in Artificial Intelligence: Biomedical Engineering Applications in Signals and Imaging provides an overview of artificial intelligence in biomedical applications, including both bio-signals and bio-imaging modalities. The chapters contain a mathematical formulation of algorithms and their applications in the biomedical eld, including case studies. Biomedical engineers, advanced students, and researchers can use this book to apply their knowledge in artificial intelligence-based processes to biological signals, implement mathematical models and advanced algorithms, and develop AI-based medical devices.
In this issue of Dermatologic Clinics, guest editor Dr. Hassan Galadari brings his considerable expertise to the topic of Hot Topics in Cosmetic Dermatology. Top experts cover key topics such as neurotoxin in the lower third of the face; chemical peels in the treatment of melasma; management of under eye darkness and wrinkles; facial overfilled syndrome; the needle vs. cannula debate in soft tissue augmentation; achieving the attractive Asian midface profile with hyaluronic acid-based fillers; and more.Contains 17 relevant, practice-oriented topics including updates on lasers in dermatology; update in assessment and treatment of botulinum toxin in the upper face; cosmetic dermatology in skin of color; management of cellulite; the effect of cosmetic procedures on the youth; and more.Provides in-depth clinical reviews on hot topics in cosmetic dermatology, offering actionable insights for clinical practice.Presents the latest information on this timely, focused topic under the leadership of experienced editors in the field. Authors synthesize and distill the latest research and practice guidelines to create clinically significant, topic-based reviews.
Adding Value to Fruit Wastes: Extraction, Properties, and Industrial Applications provides the latest technologies used in fruit waste to extract, isolate, and characterize functional, active compounds and their diversified pharmacological, food, agricultural, and industrial applications. Divided in three sections, the book explores emerging technologies for the extraction of functional components, discusses value-added components, and works as a guide to its applications. The book also covers fruit wastes for extracting starch to provide more cereal crops available as food, besides supporting the efficient utilization of fruit wastes to bring opportunities for extraction of functional components in a sustainable manner for food applications.Written by a team of experts in the field, this book provides technicians, researchers, food technology experts, food industry personnel, and academia with value addition to the fruit waste and a lot more opportunities for extraction of functional components in a sustainable manner for food applications.
Approximately 1 in 36 children in the United States will be diagnosed with autism spectrum disorder (ASD) and that number is expected to rise according to the CDC. Interventions based on the science of applied behavior analysis (ABA) are one of the most common interventions for autistic individuals. One of the biggest problems facing the field of ABA-based interventions is ineffectiveness of intervention approaches due to the rigid application of ABA-based interventions. Progressive Approach to Applied Behavior Analysis provides practicing behavior analysts (e.g., BCBAs, BCaBAs, RBTs) and other clinicians with an in-depth introduction to a Progressive Approach to ABA and how it applies to common teaching methods within ABA-based interventions. This includes research and guidelines for implementing a Progressive Approach to ABA, potentially increasing the likelihood of meaningful outcomes for individuals diagnosed with ASD. This will become the guide for practitioners on how to use clinical judgment and in-the-moment assessment across various procedures.
Traditional Starch Food Products: Application and Processing is the fourth volume of the "Underground Starchy Crops of South American Origin" book series. Organized in five volumes, this series brings information on the applied level of producing and using starch from a range of plants grown in tropical and subtropical areas that have South American origin. This book describes the use of starchy roots, tubers and rhizomes in food, medicine, local culture, and religion, emphasizing the vital roles they play in indigenous Andean or Amazonian communities, offering cultural identity and economic value. The book’s comprehensive exploration highlights the multifaceted world of underground starchy crops, emphasizing the challenges to their successful development and preservation. Edited by a team of experts with solid background on starch extraction research, these books are aimed at all those involved in research and development, new technology processes and quality control and legislation in the field of starch.
Thoracic surgery has evolved substantially in recent years, with tremendous advancements in minimally invasive surgical procedures, novel techniques for sublobar resection, perioperative management, and more. Thoracic Surgery Atlas, 2nd Edition, written by Dr. Mark K. Ferguson, brings you fully up to date with all aspects of this fast-changing field. Comprehensive and highly illustrated, this general thoracic surgery text covers procedures involving all chest organs (lungs, esophagus, trachea, mediastinum, chest wall, and diaphragm), offering authoritative guidance on virtually any thoracic operation you're likely to perform-from cancer surgery to management of a variety of benign conditions, including esophageal disorders, empyema, tracheal stricture, and much more. Includes authoritative, experience-based observations to help guide you through details of complex procedures, avoid common problems, and manage complications when they occur. Features numerous high-quality, original color and tone drawings that depict the relevant anatomy and steps associated with each procedure. Expands coverage to include new areas of thoracic surgery, new and updated illustrations, and new content and references throughout. Provides new information on ERAS protocol summaries for perioperative care, consensus guidelines for essential steps in minimally invasive lung resection, new surgical approaches to mediastinal abnormalities, increased focus on VATS and robotic operations including uniportal surgery, new methods of treating thoracic outlet syndrome, new approaches to managing malignant ventricular arrhythmias through sympathectomy, more advanced techniques for pleurectomy for mesothelioma, and descriptions of a variety of newer muscle flaps for reconstruction. An eBook version is included with purchase. The eBook allows you to access all of the text, figures, and references, with the ability to search, customize your content, make notes and highlights, and have content read aloud.
Visualizing More Quaternions is a sequel to Dr. Andrew J. Hanson’s first book, Visualizing Quaternions, which appeared in 2006. This new volume develops and extends concepts that have attracted the author’s attention in the intervening 18 years, providing new insights into existing scholarship, and detailing results from Dr. Hanson’s own published and unpublished investigations relating to quaternion applications. Among the topics covered are the introduction of new approaches to depicting quaternions and their properties, applications of quaternion methods to cloud matching, including both orthographic and perspective projection problems, and orientation feature analysis for proteomics and bioinformatics. The quaternion adjugate variables are introduced to embody the nontrivial quaternion topology on the three-sphere and incorporate it into machine learning tasks. Other subjects include quaternion applications to a wide variety of problems in physics, including quantum computing, complexified quaternions in special relativity, and a detailed study of the Kleinian "ADE"discrete groups of the ordinary two-sphere. Quaternion geometry is also incorporated into the isometric embedding of the Eguchi-Hanson gravitational instanton corresponding to the k = 1 Kleinian cyclic group. Visualizing More Quaternions endeavors to explore novel ways of thinking about challenging problems that are relevant to a broad audience involved in a wide variety of scientific disciplines.
For more than 50 years, Dubois’ Lupus Erythematosus and Related Syndromes has been recognized internationally as the go-to clinical reference on lupus and other connective tissue diseases. From basic scientific principles to practical points of clinical management, the 10th edition provides extensive, authoritative coverage of systemic lupus erythematosus (SLE) and its related diseases in a logical, clearly written, user-friendly manner. It’s an ideal resource for rheumatologists and internal medicine practitioners who need a comprehensive clinical reference on all aspects of SLE, connective tissue diseases, and the antiphospholipid syndromes.Provides complete clinical coverage of every aspect of cutaneous and systemic lupus erythematosus, including definitions, pathogenesis, autoantibodies, clinical and laboratory features, management, prognosis, and patient education.Includes significant new content throughout: a new chapter on the endocrine system and hormones; newly distinct chapters on the heart and lung; new content on social disparities in lupus, clinical presentation of nephritis, and pulmonary hypertension; a new concluding chapter on future directions in the field; new basic science coverage of the microbiome, autoinflammatory, and monogenic lupus; and new coverage of diversity, inclusion, gender, compliance, and adherence.Offers a fresh perspective from two new associate editors and many new authors with representation from 30 countries.Contains an up-to-date overview of significant advances in cellular, molecular, and genetic technologies, including genetic advancements in identifying at-risk patients.Discusses the clinical management of related disorders such as Sjogren’s syndrome, scleroderma, polymyositis, and antiphospholipid syndrome (APS).Presents the knowledge and expertise of international contributors to provide new global perspectives on manifestations, diagnosis, and treatment.Features a vibrant, full-color format, with graphs, algorithms, differential diagnosis comparisons, new and improved figures, and schematic diagrams throughout.An eBook version is included with purchase. The eBook allows you to access all of the text, figures, and references, with the ability to search, customize your content, make notes and highlights, and have content read aloud. Additional digital ancillary content may publish up to 6 weeks following the publication date.
Handbook of Translational Transcriptomics: Research, Protocols and Applications provides a comprehensive overview on the field of transcriptomics. The book begins with an overview of the past, present, and potential approaches in the field of transcriptomics, with discussions on choosing the correct approach based on the research needed. The book also highlights the pros and cons of each approach and explores techniques and protocols for investigating specific avenues, focusing on RNA sequencing, expression arrays, and gene expression. Sections on data analysis offer recommendations, guidelines, and approaches related to data interpretation.The book also considers the translation of transcriptomics to clinical application and applications in molecular diagnostics, biomarkers in medicine, and personalized medicine specific to oncology, as well as biotechnology for pharmaceutical research.
Marine Bivalve Mollusks and Emerging Pollutants: Toxicological Impacts provides the most updated and comprehensive knowledge of the toxicological impacts of a variety of emerging pollutants on marine bivalve mollusk species. In addition to synthesizing recent toxicological findings, the book also discusses toxification mechanisms, current challenges, and future research prospects. Written by international experts, this book assesses new advances in the toxicological impacts of pollutants, including microplastics, bromide flame retardants, nanomaterials, pharmaceutical residues, personal care products, pesticides, and perfluorinated compounds. In addition, it details how these can affect reproduction, embryonic development, metabolism, and immune systems of marine bivalves. Behavioral responses and neuroendocrine regulation is also discussed. Toxification mechanisms are interpreted at both physiological and molecular levels. The book concludes with current research and environmental challenges and potentials for further, future study techniques.
In Neuroscience Without Representations, an Open Access book, Oscar Vilarroya addresses the notion of "representation" as used in expressions like "neural representation" or "mental representation". This concept is fundamental in neuroscience, yet there remains no clear, universally accepted view on what it means for a nervous system to represent something, what constitutes a neural activity as a representation, and what is being re-presented. The book lays the foundation for a non-representational view of brain function. Building upon György Buzsáki’s critique of the theoretical framework underlying current cognitive neuroscience, Vilarroya argues that disciplines such as embodied and embedded cognition-collectively known as ‘4E cognition’-are driving a paradigm shift in our understanding of animal cognition. Rather than grounding cognition solely in representations, the author proposes an alternative: understanding cognition as enaction-the meaningful engagement of an organism to address situational requirements. The book supports this approach through detailed analyses of recent studies.
Microbial Genomics: Clinical, Pharmaceutical and Industrial Applications focuses on the various applications of microbial genomics in clinical, pharmaceutical, and industrial fields. The book consists of four parts devoted to bacterial, viral, and fungal genomics, as well as their applications in clinical, pharmaceutical, and industrial fields. Chapters are written by experts in their respective disciplines and are tightly organized with an introduction to detailed descriptions, available software implementation, applications, advanced topics, summaries, analytic questions, exercises, and suggested readings. Throughout this book, the latest genomics and biotechnological developments and discoveries as well as open problems and future challenges on microbial genomics are highlighted. Readers will be introduced to state-of-the-art developments and trends of microbial genomics, its clinical, pharmaceutical, and industrial applications.
Magnetoelectric Composites: Materials, Structures, and Applications, Second Edition summarizes the theory behind magnetoelectric phenomena and then introduces magnetoelectric materials and structures and the techniques used to fabricate and characterize them. Part two of the book looks at magnetoelectric devices: applications covered include magnetoelectric sensors, magnetoelectric antennas, transducers for energy harvesting, microwave and millimetre wave devices, and miniature magnetoelectric systems for biomedical applications. The final chapter discusses progress toward magnetoelectric memory.This new edition starts with the phenomena and theory of magnetoelectric materials in bulk laminates, thin-film heterostructures, and nanocomposites. On the magnetoelectric devices side, the contents have been significantly expanded to include energy harvesting, sensing, and magnetoelectric antennas. This book is suitable for materials scientists and engineers working on magnetoelectrics in academia and R&D.
Machine Learning Applications in Industrial Solid Ash begins with fundamentals in solid ash, covering the status of solid ash generation and management. The book moves on to foundational knowledge on ML in solid ash management, which provides a brief introduction of ML for solid ash applications. The reference then goes on to discuss ML approaches currently used to address problems in solid ash management and recycling, including solid ash generation, clustering analysis, origin identification, reactivity prediction, leaching potential modelling and metal recovery evaluation, etc. Finally, potential future trends and challenges in the field are discussed. Offering the ability to process large or complex datasets, machine learning (ML) holds huge potential to reshape the whole status for solid ash management and recycling. This book is the first published book about ML in solid ash management and recycling. It highlights fundamental knowledge and recent advances in this topic, offering readers new insight into how these tools can be utilized to enhance their own work.
Metabolomics for Personalized Vaccinology provides insight into the importance of personalized vaccines in the clinical and research environments. It explores the development of personalized vaccines, which requires in-depth knowledge of the patient's health status, particularly the immune system, and on metabolomics, the closest indicator of the disease phenotype. Specifically, the book provides an understanding of how metabolomics might be employed in personalized vaccinology and how the metabolic pathway of the host's system is altered by vaccine administration.Over the past few years, researchers have published articles on personalized vaccines, but these are sparse. Therefore, compiling information on this topic gives the reader an overview of the progress of the field, despite being at its infancy.Metabolomics for Personalized Vaccinology is ideally suited for researchers and postgraduate students who are interested in clinical and nonclinical studies where metabolites are used for the identification of disease and therapeutic targets.
Functionalized Nanomaterials for Cancer Research: Applications in Treatments, Tools and Devices presents an in-depth and step-by-step description of knowledge on functionalized nanomaterials for cancer research, including treatment and future developments as well as their impact on patients’ overall outcomes. The book discusses functionalized nanoplatforms for cancer detection and imaging, interactions between nanomaterials and cancer cells, and drug resistant malignancies. The book's chapters are organized in a manner that can be readily adopted as sources for new and further studies by highlighting the main in vitro and in vivo nano-therapeutic achievements on cancer. Additionally, current trends on functionalized nanomaterials for cancer research and commercial scale opportunities are discussed. This is a valuable resource for researchers, oncologists, students, and members of the biomedical and medical fields who want to learn more about the potential of nanotechnology in cancer research and treatment.
Nanostructured Drug Delivery Systems in Infectious Disease Treatment explores a broad range of promising approaches for the treatment of infectious diseases using the latest advancements in nanomedical technologies. The book opens with an introduction about infectious diseases and global burdens. There is also specific discussion and assessment of the global impact of viruses with an emphasis on COVID-19, Zika, and Ebola. Subsequent chapters provide detailed information about various novel nanotherapeutic strategies used for delivering drugs for the treatment of various types of viral, bacterial, and fungal disorders. This will be a valuable resource for graduates, researchers, industry professionals, and anyone working to tackle the challenges of delivering drugs in a more targeted and efficient manner for the treatment of infectious diseases.
"This expert volume in the Diagnostic Pathology series is an excellent point-of-care resource for practitioners at all levels of experience and training. Covering all aspects of infectious diseases, including novel infections and lesser-known microorganisms, this volume incorporates the most recent scientific and technical knowledge in the field to provide a comprehensive overview of all key issues relevant to today's practice. Richly illustrated and easy to use, the third edition of Diagnostic Pathology: Infectious Diseases is a visually stunning, one-stop resource for every practicing pathologist, resident, student, or fellow as an ideal day-to-day reference or as a reliable training resource"--
Inherited White Matter Disorders and Their Mimics, Volume 204 discusses where imaging abnormalities and pathology lie predominantly in the CNS white matter. Many acquired causes, such as multiple sclerosis, are readily diagnosed and familiar to the majority of neurologists. However, less common acquired causes and genetic disorders (the leukodystrophies and genetic leukoencephalopathies) often present a diagnostic challenge. The evaluation of patients with White matter disorders (WMDs) has evolved enormously in recent decades, due to advances in genetics, radiology, and the development of treatments for specific disorders. This book brings together WMD research, spanning basic science, molecular genetics, and clinical and radiological phenotyping.This volume presents both common WMDs and rare disorders according to their presentations or pathophysiology. Chapters lay out the clinical and radiological presentation of the disorder, followed by genetics and diagnostics, and finally discussion of pathophysiology and treatment. Chapter contain imaging, clinical pearls to diagnosis, and reference tables for genotype-phenotype correlation. For diagnostic work-up, easy to read algorithms are presented as well as clear guidance on indications for treatment, where applicable.
Neurological Channelopathies, Volume 203 begins with an introductory overview highlighting common mechanistic themes that cut across different CNS and PNS presentations, but that also have potential for common treatment approaches, considering classification, genetics, and fundamental physiology of ion channels. Subsequent chapters present a detailed consideration of all genetic and immunological channelopathies. Each chapter considers Pathophysiological underpinnings - genetic or immunological; Clinical presentations; Diagnostic approach; and Treatment and management.In the last 15 years, a combination of detailed clinical, genetic, molecular electrophysiological, and immunological research has combined to result in a deep understanding of a subgroup of neurological diseases spanning the central and peripheral nervous system and which have become known collectively as the Neurological Channelopathies. Although it was originally considered that significant ion channel dysfunction would not be compatible with life, we now know this is often not the case, although severe disease can often be the result. Given these major advances, it is now the right time to combine this knowledge into a single HCN volume dedicated to the topics at hand.
Computational Modeling Applications for Climate Crisis provides readers with innovative research on the applications of computational modeling to moderate climate change. The book begins with an overview and history of climate change, followed by several chapters covering the concepts of computational modeling and simulation, including parameters of climate change, modeling the effects of human activities, visualization tools, and data fusion for advanced modeling applications. It then proceeds to cover decision support systems, modeling of technological solutions for climate change, modeling of greenhouse gas emissions, tracking of climate factors, and modeling of earth resources. In the final chapters of the book, the authors cover nation-based outcomes, big data, and optimization solutions with real-world data and case studies. Climate change is one of the most pressing existential issues for humans and the planet, and this book covers leading-edge applications of computational modeling to the vast array of interdisciplinary factors and challenges posed by climate change. As life itself is a mixture of occurrences that can be mathematically modelled, it is important to work with specific parameters, which are critical for monitoring and controlling the dynamics of the earth, natural resources, technological factors, and human activities.
Treatment and Utilization of Combustion and Incineration Residues introduces state-of-art strategies for combustion and incineration solid residue management and utilization. The book also reviews current technologies for pollutant removal and control of combustion and incineration residues. Recycling ashes and slags in sustainable construction materials are also evaluated on environmental impacts and engineering values, and the use of different ashes and slags in cement clinker production is classified based on the sources and properties of the residues. In addition, the recovery of valuable metals and inorganic elements is also discussed.Finally, the book examines the latest understanding of reaction mechanisms of various treatment technologies, the future design of treatment technologies, and the actualization of sustainable management for combustion/incineration residues.
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