Böcker utgivna av IntechOpen

Leishmania parasites plague the mammalian host causing high morbidity and mortality. The parasites persist in the hostile milieu, crippling its defensive arsenal. In the face of mounting resistance to an antiquated drug arsenal, new approaches are urgently desired to keep the infection at bay. Furthermore, to strengthen the leishmaniasis elimination drive, particular emphasis has to be laid on identification of new targets and vaccination strategies. This book gives a brief glimpse of the epidemiology of leishmaniasis, immune evasion, vaccination, and therapeutic modalities that may work by untangling the immunological cross-wires of pathogenic cross-talk. The Conventional treatment and its drawbacks, the prospects of phytotherapy and nanomedicines, are also discussed. The identification of drug targets with the aim of designing inhibitors is also exemplified.

As a strategic response to cognitive and CNS impairments, BCI is a theoretical outgrowth of several generations of endogenous devices for peripheral nerves, which have as a prime goal the direct replacement of lost neural function. In these earlier applications therapeutic intervention has been premised only on the restoration of signal generating capacity where nerve transmission is largely unidirectional and temporally sequenced. It is increasingly apparent, however, that the brain not only employs a very different type of syntax from that of peripheral nerves but also structures the semantic content of motor activity, fundamentally altering the conception of BCI as a therapeutic medium. The book presented here documents this change, proposing a multi-faceted strategy in which BCI therapy can restore the loss of multi-tiered, brain based motor function.

Renewable energy is the answer for future energy demand. Renewable energy is the energy that occurs in a natural manner and utilizes unlimited resources. It is the solution for reducing the dependence on fossil fuels and diminishing greenhouse gas emission. It is the key for cleaner, greener, and sustainable energy. In today's world, increased energy needs and environmental and health concerns associated with traditional energy systems have made way for rapid progress in producing energy from renewable resources. However, large-scale integration of current technologies and newer approaches are still required for more efficient and cost-effective systems. This small book is a collection of single research chapters dealing with biofuel generation and some recent methods for grid integration and storage problems. The editors would like to record their sincere thanks to the authors for their contributions.

Most leaders of developed nations recognize the importance of following policies and strategies to achieve a low-carbon economy based on new and innovative technologies that are able to reduce greenhouse gas emissions and create new employment and growth. In the broad spectrum of the feasible decarbonisation pathways, the challenge for political and economic decision-makers is to weigh uncertain impact from different technologies and to build a comprehensive evidence-based framework for research, business, investment and policy decision-making. This book aims to provide the reader with a comprehensive overview of the current state-of-the-art technology in the Low Carbon Technology and Economy field, discussing a set of new technology approaches and environmental and economic implications.

Rapid tests, also known as point-of-care tests, have been in use for decades in the clinical and medical area and have become increasingly popular as an efficient screening method for conducting on-site analysis thanks to their simplicity, speed, specificity and sensitivity. Nowadays, rapid tests are widely applied for clinical, drug, food, forensic and environmental analysis and fields of application are rapidly increasing together with advances in the technology. The growing interest in rapid tests and their expanding application in diverse fields, together with requirements of improved sensitivity, reliability, multiple detection capacity and robustness, are prompting innovation in the design of novel platforms, and in the exploitation of innovative detection strategies. The book covers advances in materials, technology and test design.