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On August 16, 2000, the Board on Life Sciences held a forum on "Environmental Contamination, Biotechnology, and the Law: The Impact of Emerging Genomic Information." The purpose of the forum was to explore the legal implications of current and developing biotechnology approaches to evaluating potential human health and environmental effects caused by exposure to environmental contaminants and to cleaning up contaminated areas. The forum brought together scientists from academe, government, and industry and members of the legal community, including lawyers and judges, to discuss the interface between the use of those approaches and the legal system.

At the request of the Chief of Naval Operations, the National Research Council, under the auspices of the Naval Studies Board, established a committee to assess the Department of the Navy's current and future naval theater missile defense (TMD) capabilities. The Committee for Naval Forces' Capability for Theater Missile Defense first convened in April 2000 and met approximately 2 days a month for 8 months. This report is based on the information presented to the committee during that period and on the committee members' accumulated experience and expertise in military operations, systems, and technologies.

In 1996 the Federal Accounting Standards Advisory Board (FASAB) 1 enacted Standard Number 6, Accounting for Property, Plant, and Equipment (PP&E), the first government-wide initiative requiring federal agencies to report dollar amounts of deferred maintenance annually. The FASAB has identified four overall objectives in federal financial reporting: budgetary integrity, operating performance, stewardship, and systems and control. FASAB Standard Number 6, as amended, focuses on operating performance and stewardship. The FFC Standing Committee on Operations and Maintenance has prepared this report to identify potential issues that should be considered in any future amendments to the standard and to suggest approaches for resolving them. The committee's intent is to assist the CFO Council, federal agencies, the FASAB, and others as they consider how best to meet the objectives of federal financial reporting for facilities.

The National Research Council's Committee on Atmospheric Chemistry (NRC/CAC) was established to serve as a focal point for NRC activities on issues related to atmospheric chemical change and its impacts on air quality, climate, stratospheric ozone depletion, and other related issues. The committee consists of 12 members with expertise covering the areas of tropospheric and stratospheric chemistry; urban/regional air pollution; modeling of climate, chemistry, and atmospheric dynamics; in situ and remote sensing observational systems; and interfaces of science and public policy. This CAC study was motivated by a concern that, in the coming decades, dramatic increases in global population and urbanization levels, as well as changes in global climate, may significantly affect air quality over large regions of the globe. The charge to the committee was to examine the linkages among regional/ global changes in atmospheric composition, climate change, and air quality.

The high latitudes of the Arctic and Antarctic, together with some mountainous areas with glaciers and long-lasting snow, are sometimes called the cryosphere-defined as that portion of the planet where water is perennially or seasonally frozen as sea ice, snow cover, permafrost, ice sheets, and glaciers. Variations in the extent and characteristics of surface ice and snow in the high latitudes are of fundamental importance to global climate because of the amount of the sun's radiation that is reflected from these often white surfaces. Thus, the cryosphere is an important frontier for scientists seeking to understand past climate events, current weather, and climate variability. Obtaining the data necessary for such research requires the capability to observe and measure a variety of characteristics and processes exhibited by major ice sheets and large-scale patterns of snow and sea ice extent, and much of these data are gathered using satellites. As part of its efforts to better support the researchers studying the cryosphere and climate, the National Aeronautics and Space Administration (NASA)-using sophisticated satellite technology-measures a range of variables from atmospheric temperature, cloud properties, and aerosol concentration to ice sheet elevation, snow cover on land, and ocean salinity. These raw data are compiled and processed into products, or data sets, useful to scientists. These so-called "polar geophysical data sets" can then be studied and interpreted to answer questions related to atmosphere and climate, ice sheets, terrestrial systems, sea ice, ocean processes, and many other phenomena in the cryosphere. The goal of this report is to provide a brief review of the strategy, scope, and quality of existing polar geophysical data sets and help NASA find ways to make these products and future polar data sets more useful to researchers, especially those working on the global change questions that lie at the heart of NASA's Earth Science Enterprise.

In response to HUD's request, the NRC assembled a panel of experts, the Committee for Oversight and Assessment of the Partnership for Advancing Technology in Housing, under the auspices of the Board on Infrastructure and the Constructed Environment. Over an initial term of three years, the committee was asked to review and comment on the following aspects of the PATH program: overall goals; proposed approach to meeting the goals and the likelihood of achieving them; and measurements of progress toward achieving the goals.

Aquifer storage and recovery (ASR) is a process by which water is recharged through wells to an aquifer and extracted for beneficial use at some later time from the same wells. ASR is proposed as a major water storage component in the Comprehensive Everglades Restoration Plan (CERP), developed jointly by the U.S. Army Corps of Engineers (USACE) and the South Florida Water Management District (SFWMD). The plan would use the Upper Floridan aquifer (UFA) to store as much as 1.7 billion gallons per day (gpd) (6.3 million m3/day) of excess surface water and shallow groundwater during wet periods for recovery during seasonal or longer-term dry periods, using about 333 wells. ASR represents about one-fifth of the total estimated cost of the CERP. Aquifer Storage and Recovery in the Comprehensive Everglades Restoration Plan examines pilot project from the perspective of adaptive assessment, i.e., the extent to which the pilot projects will contribute to process understanding that can improve design and implementation of restoration project components. This report is a critique of the pilot projects and related studies.

This report is intended to promote a dialogue between the scientific community and the government officials who will lead our nation in the coming years on global change research. The first section of the report is a brief description of the challenges and proposed responses needed from the highest levels of the government and the second provides more detailed discussion and is directed to agency-level issues and responses. The last section is a detailed bibliography that lists many of the specific reports on which the views outlined here are ultimately based.

The National Research Council's Committee on the Impact of Low-Level Radioactive Waste Management Policy on Biomedical Research in the United States was called on to assess the effects of the low-level radioactive waste management policy on the current and future activities of biomedical research. This report provides an assessment of the effects of the current management policy for low-level radioactive waste (LLRW), and resulting consequences, such as higher LLRW disposal costs and onsite storage of LLRW, on the current and future activities of biomedical research. That assessment will include evaluating the effects that the lack of facilities and disposal capacity, and rules of disposal facilities, have on institutions conducting medical and biological research and on hospitals where radioisotopes are used for the diagnosis and treatment of disease.

Proponents of agricultural biotechnology believe that genetically modified (GM) crops have the potential to provide great ecological benefits, such as reduced pesticide and land use, as well as agricultural benefits. However, given the rapid emergence of commercial GM crops and the likely increase in their use, many groups have raised concerns about the potential unintended, adverse ecological effects of these crops. Some ecological concerns are enhanced development of pest resistance, crosspollination with wild relatives, and reductions in beneficial insects or birds. Ecological Monitoring of Genetically Modified Crops considers the latest in monitoring methods and technologies and to asks--What are the challenges associated with monitoring for ecological effects of GM crops? Is ongoing ecological monitoring of GM crops a useful and informative activity? If so, how should scientifically rigorous monitoring be carried out in the variety of ecological settings in which GM crops are grown?

Since 1992, the Committee on National Statistics (CNSTAT) has produced a book on principles and practices for a federal statistical agency, updating the document every 4 years to provide a current edition to newly appointed cabinet secretaries at the beginning of each presidential administration. This second edition presents and comments on three basic principles that statistical agencies must embody in order to carry out their mission fully: (1) They must produce objective data that are relevant to policy issues, (2) they must achieve and maintain credibility among data users, and (3) they must achieve and maintain trust among data providers. The book also discusses 11 important practices that are means for statistical agencies to live up to the four principles. These practices include a commitment to quality and professional practice and an active program of methodological and substantive research.

At the request of the Department of Education, the National Research Council formed the Committee on NAEP Reporting Practices to address questions about the desirability, feasibility, and potential impact of implementing these reporting practices. The committee developed study questions designed to address issues surrounding district-level and market-basket reporting.

The Institute of Medicine's (IOM's) Food Forum was established in 1993 to allow science and technology leaders in the food industry, top administrators in several federal government agencies from the United States and Canada, representatives from consumer interest groups, and academicians to openly communicate in a neutral setting. The Food Forum provides a mechanism for these diverse groups to discuss food, food safety, and food technology issues and to identify possible approaches for addressing these issues by taking into consideration the often complex interactions among industry, regulatory agencies, consumers, and academia. The objective, however, is to illuminate issues, not to resolve them. Unlike study committees of the IOM, forums cannot provide advice or recommendations to any government agency or other organization. Similarly, workshop summaries or other products resulting from forum activities are precluded from reaching conclusions or recommendations but, instead, are intended to reflect the variety of opinions expressed by the participants. On July 13-14, 1999, the forum convened a workshop on Food Safety Policy, Science, and Risk Assessment: Strengthening the Connection. The purpose of the workshop was to address many of the issues that complicate the development of microbiological food safety policy, focusing on the use of science and risk assessment in establishing policy and in determining the utilization of food safety resources. The purpose was not to find fault with past food safety regulatory activities or food safety policy decisions. Rather, the goal was to determine what actions have been taken in the past to address food safety issues, to consider what influences led to the policies that were put in place, and to explore how improvements can be made in the future. This report is a summary of the workshop presentations. It is limited to the views and opinions of those invited to present at the workshop and reflects their concerns and areas of expertise. As such, the report does not provide a comprehensive review of the research and current status of food safety policy, science, and risk assessment. The organization of the report approximates the order of the presentations at the workshop. The identification of a speaker as an "industry representative" or a "Food and Drug Administration representative" is not intended to suggest that the individual spoke for that organization or others who work there.

The Committee on Educational Excellence and Testing Equity was created under the auspices of the National Research Council (NRC), and specifically under the oversight of the Board on Testing and Assessment (BOTA). The committee's charge is to explore the challenges that face U.S. schools as they work to achieve the related goals of academic excellence and equity for all students. This report provides not only the summary of a workshop held by the forum on the testing of English-language learners (students learning English as an additional language) in U.S. schools, but also a report on the committee's conclusions derived from that workshop and from subsequent deliberations.

In the Bhopal disaster of 1984, approximately 2,000 residents living near a chemical plant were killed and 20,000 more suffered irreversible damage to their eyes and lungs following the accidental release of methyl isocyanate. This tragedy served to focus international attention on the need for governments to identify hazardous substances and assist local communities in planning how to deal with emergency exposures. Since 1986, the U.S. Environmental Protection Agency has been tasked with identifying extremely hazardous substances and, in cooperation with the Federal Emergency Management Agency and the Department of Transportation, assist local emergency response planners. The National Advisory Committee on Acute Exposure Guideline Levels for Hazardous Substances was established in 1995 to develop acute exposure guideline levels (AEGLs) for high priority toxic chemicals that could be released into the air from accidents at chemical plants, storage sites, or during transportation. This book reviews toxicity documents on five chemicals--chlorine, hydrogen chloride, hydrogen fluoride, toluene, and uranium hexafluoride--for their scientific validity, comprehensives, internal consistency, and conformance to the 1993 guidelines report.

In this first in a proposed series of workshops on regulatory issues in animal care and use, the Institute for Laboratory Animal Research (ILAR) has addressed the existing and proposed requirements for reporting pain and distress in laboratory animals. The Animal Welfare Act, administered by the Animal and Plant Health Inspection Service of the United States Department of Agriculture (USDA), mandates that pain and distress in laboratory animals be minimized. USDA is considering two policy changes with regard to this specific mandate. Firstly, since there has been no functional definition of "distress," USDA has prepared such a definition and requested feedback from the scientific community on its usefulness for regulatory and reporting requirements. The second issue concerns the pain and distress categorization scheme for reporting to USDA. Various groups and individuals have questioned the efficacy of the current categories, and specific changes have been proposed by the Humane Society of the United States. USDA is considering these and other potential changes to the existing scheme. Thus, given these potential changes to animal welfare policy, the aim of the ILAR/NIH joint workshop was to provide feedback to the USDA. The speakers were asked to address these two issues as well as to comment upon whether the information contained in the 1992 ILAR report Recognition and Alleviation of Pain and Distress in Laboratory Animals is still useful to investigators in assisting them to comply with regulations. The speakers provided perspectives based on their individual expertise in the areas of science of pain and distress, animal welfare policy, protocol review, and/or as representatives of relevant organizations or institutions. The following proceedings are an edited transcript of their presentations.

The goal of this workshop was to bring together bioinformatics stake holders from government, academe, and industry for a day of presentations and dialogue. Fifteen experts identified and discussed some of the most important issues raised by the current flood of biologic data. Topics explored included the importance of database curation, database integration and interoperability, consistency and standards in terminology, error prevention and correction, data provenance, ontology, the importance of maintaining privacy, data mining, and the need for more computer scientists with specialty training in bioinformatics. Although formal conclusions and recommendations will not come from this particular workshop, many insights may be gleaned about the future of this field, from the context of the discussions and presentations described here.

The National Research Council was asked by the Centers for Disease Control and Prevention (CDC) to review the draft report of the National Cancer Institute (NCI)-CDC's working group charged with revising the 1985 radioepidemiological tables. To this end, a subcommittee was formed consisting of members of the Council's Committee on an Assessment of the Centers for Disease Control and Prevention Radiation Programs and other experts. The original tables were mandated under Public Law 97-414 (the "Orphan Drug Act") and were intended to provide a means of estimating the probability that a person who developed any of a series of radiation-related cancers, developed the cancer as a result of a specific radiation dose received before the onset of the cancer. The mandate included a provision for periodic updating of the tables. The motivation for the current revision reflects the availability of new data, especially on cancer incidence, and new methods of analysis, and the need for a more thorough treatment of uncertainty in the estimates than was attempted in the original tables.

The Food and Nutrition Board of the Institute of Medicine (IOM), part of the National Academies, was asked to evaluate the use of various dietary assessment tools and to make recommendations for the assessment of inadequate or inappropriate dietary patterns. These assessments should accurately identify dietary risk of individuals and thus eligibility for participation in the Special Supplemental Nutrition Program for Women, Infants, and Children (WIC). The Committee on Dietary Risk Assessment in the WIC Program was appointed for the 2-year study and directed to develop an interim report which was to include (1) a framework for assessing inadequate diet or inappropriate dietary patterns, (2) a summary of a workshop on methods to assess dietary risk, and (3) the results of literature searches conducted to date. This interim report includes these three components. Building on the approach used in the 1996 IOM report, WIC Nutrition Risk Criteria, the framework proposed by the committee identifies characteristics of dietary assessment tools that can identify dietary patterns or behaviors for which there is scientific evidence of increased nutrition or health risk in either the short or long-term. The proposed framework consists of eight characteristics that a food intake and/or behavior-based tool should have when used to determine eligibility to participate in WIC programs. This interim report also includes authored summaries of the presentations at the workshop, along with the results of literature searches conducted in the initial phase of the study.

US/Japan meetings on laboratory animal science have been held virtually every year since 1980 under the US/Japan Cooperative Program on Science and Technology. Over the years these meetings have resulted in a number of important documents including the Manual of Microbiologic Monitoring of Laboratory Animals published in 1994 and the article Establishment and Preservation of Reference Inbred Strains of Rats for General Purposes. In addition to these publications, the meetings have been instrumental in increasing awareness of the need for microbiologic monitoring of laboratory rodents and the need for genetic definition and monitoring of mice and rats. In cooperation with the Comparative Medicine section of NCRR/NIH, the ILAR Council and staff are pleased to become the host for this important annual meeting and look forward to participating in future meetings. The support and sponsorship of NCRR (P40 RR 11611) in the United States and the Central Institute for Experimental Animals in Japan are gratefully acknowledged. Bringing together the leading scientists in the field of laboratory animal care has resulted in increased understanding of American and Japanese approaches to laboratory animal science and should continue to strengthen efforts to harmonize approaches aimed at resolving common challenges in the use of animal models for biomedical research and testing. This effort to improve understanding and cooperation between Japan and the United States should also be useful in developing similar interaction with other regions of the world including Europe, Australia, and Southeast Asia.

Since the Gulf War ended in 1991, various constituencies, including a significant number of veterans, speculate that unidentified risk factors led to chronic, medically unexplained illnesses, and these constituencies challenge the depth of the military's commitment to protect the health of deployed troops. Despite general concurrence in findings to support these claims, few changes have been made at the field level. The most important recommendations remain unimplemented, despite the compelling rationale for urgent action. Protecting Those Who Serve illuminates these recommendations and government-developed plans that remain inactive due to a lack of authority within the Department of Defense, while describing the dangers that may result from failure to protect our forces in the field.

The Panel on Juvenile Crime: Prevention, Treatment, and Control convened a workshop on October 2, 1998, to explore issues related to educational performance, school climate, school practices, learning, student motivation and commitment to school, and their relationship to delinquency. The workshop was designed to bring together researchers and practitioners with a broad range of perspectives on the relationship between such specific issues as school safety and academic achievement and the development of delinquent behavior. Education and Delinquency reviews recent research findings, identifies gaps in knowledge and promising areas of future research, and discusses the need for program evaluation and the integration of empirical research findings into program design.

This report summarizes the presentations and discussion at a workshop entitled Opportunities to Promote Child and Adolescent Development During the After-School Hours, convened on October 21, 1999. The workshop was organized by the Board on Children, Youth, and Families and its Forum on Adolescence of the National Research Council and the Institute of Medicine, with funding from the David and Lucile Packard Foundation. This workshop brought together policy makers, researchers, and practitioners to examine research on the developmental needs of children and adolescents--ages 5 to 14 years--and the types of after-school programs designed to promote the health and development of these young people. Intended to provide a forum for discussion among the various stakeholders, the workshop did not generate conclusions about the types of programs that are most effective, nor did it generate specific recommendations about after-school programs or promote a particular approach. The workshop coincided with release of the Packard Foundation's fall 1999 issue of The Future of Children, entitled "When School Is Out." Focusing on after-school programs, the journal provided some context for the workshop, providing a backdrop for discussing the importance of after-school programs, the types of programs that exist across the country, and the policy climate that surrounds after-school programs. This report summarizes the workshop.

Research Council established the Ecosystems Panel in response to a request from the United States Global Change Research Program (USGCRP). The panel's charge included periodic reviews of the ecosystems aspects of the USGCRP, and this is the first of those reviews. It is based on information provided by the USGCRP, including Our Changing Planet (NSTC 1997 and earlier editions 1); ideas and conversations provided by participants in a workshop held in St. Michaels, Maryland, in July 1998; and the deliberations of the panel. In addition, the panel reviewed the ecosystems chapter of the NRC report Global Environmental Change: Research Pathways for the Next Decade (NRC 1999a, known as the Pathways report).The USGCRP is an interagency program established in 1989 and codified by the Global Change Research Act of 1990 (PL 101-606). The USGCRP comprises representatives of the departments of Agriculture, Commerce (National Oceanic and Atmospheric Administration and National Institute of Standards and Technology), Defense, Energy, Health and Human Services (theNational Institute of Environmental Health Sciences), Interior, and State, as well as the Environmental Protection Agency, the National Aeronautics and Space Administration, the National Science Foundation, the Smithsonian Institution, the Office of Science and Technology Policy, the Office of Management and Budget, and the intelligence community (NSTC 1997). The USGCRP's research program is described in detail in Our Changing Planet (NSTC 1997, 1999). In brief, the program focuses on four major areas of earth-system science: 1) Seasonal to interannual climate variability; 2) Climate change over decades to centuries; 3) Changes in ozone, ultraviolet (UV) radiation, and atmospheric chemistry, and 4) Changes in land cover and in terrestrial and aquatic ecosystems. The fourth topic is the area in which advice was requested from the ecosystems panel.The Ecosystems Panel's charge has three parts: to provide a forum for the discussion of questions of ecosystem science of interest to scientists in and out of the federal agencies, to periodically review the ecosystem aspects of the USGCRP's research program, and to help identify general areas of ecosystem science that need additional attention, especially areas that cut across ecosystems and levels of ecological organization. In addressing the second item of its charge for this report, the panel first identified the most significant and challenging areas in ecosystem science, then used that identification as a basis to make recommendations to the USGCRP. Thus, this report is not a detailed review of the USGCRP's program, but rather an attempt to identify those areas that the panel concludes are most in need of attention by a general research program on global change. As noted in this report, some of those areas are already receiving attention by the USGCRP.

The National Research Council conducted a study to identify a set of incentives that state governments and local school districts can use to attract Ph.D. scientists and mathematicians to secondary school teaching positions. This project investigated the career ambitions of Ph.D.s in the physical and life sciences through focus groups and a national survey to determine the kinds of work conditions and compensation packages that would induce them to take positions teaching physics, chemistry, biology, and various electives in public high schools or positions developing secondary school science and mathematics curricula. The study conducted interviews with Ph.D.s who are already teaching in secondary schools to ascertain information from their experiences, with local school district administrators to assess what they are realistically willing to offer Ph.D. scientists to attract them, and with higher education administrators to explore programmatic changes they would need to institute to provide Ph.D.s with skills tailored to secondary school teaching. These investigations led to this report which describes the incentives local school districts could use in establishing pilot programs in this area.

Interdisciplinary research is a cooperative effort by a team of investigators, each an expert in the use of different methods and concepts, who have joined in an organized program to attack a challenging problem. Each investigator is responsible for the research in their area of discipline that applies to the problem, but together the investigators are responsible for the final product. The need for interdisciplinary training activities has been detailed over the last 25 years in both public and private reports. The history of science and technology has even shown the important advances that arose from interdisciplinary research, including plate tectonics which brought together geologists, oceanographers, paleomagnetists, seismologists, and geophysicists to advance the ability to forecast earthquakes and volcanic eruptions.In recognition of this, the need to train scientists who can address the highly complex problems that challenge us today and fully use new knowledge and technology, and the fact that cooperative efforts have proved difficult, the National Institute of Mental Health (NIMH), the National Institutes of Health (NIH) Office of Behavioral and Social Sciences Research (OBSSR), the National Institute on Nursing Research (NINR), and the National Institute on Aging (NIA) requested that an Institute of Medicine (IOM) Committee be created to complete several tasks including: examining the needs and strategies for interdisciplinary training in the brain, behavioral, social, and clinical sciences, defining necessary components of true interdisciplinary training in these areas, and reviewing current educational and training programs to identify elements of model programs that best facilitate interdisciplinary training.Bridging Disciplines in the Brain, Behavioral, and Clinical Sciences provides the conclusions and recommendations of this committee. Due to evaluations of the success of interdisciplinary training programs are scarce, the committee could not specify the "e;necessary components"e; or identify the elements that "e;best facilitate"e; interdisciplinary training. However, after reviewing existing programs and consulting with experts, the committee identified approaches likely to be successful in providing direction for interdisciplinary endeavors at various career stages. This report also includes interviews, training programs, and workshop agendas used.

Manufactured vitreous fibers (MVF), also known as synthetic vitreous fibers, are considered to be less hazardous than asbestos to human health. They are used in many thermal- and acoustical-insulation applications as an asbestos substitute or as a filtration medium. The Navy uses MVF in shipboard and onshore applications. To protect Navy personnel from harmful exposures to MVF, the U.S. Navy Environmental Health Center (NEHC) developed occupational exposure standards. The documentation assists industrial hygienists, occupational medicine physicians, and other Navy health professionals in assessing and controlling the health hazards linked with exposure to MVF.In 1997, the National Research Council (NRC) was asked to conduct an independent review of the Navy's toxicological assessment of MVF and to evaluate the scientific validity of its exposure standard of 2 fibers per cubic centimeter of air (f/cm3). The NRC assigned the task to the Committee on Toxicology, which established the Subcommittee on Manufactured Vitreous Fibers, a multidisciplinary group of experts, to determine whether all relevant toxicological and epidemiological data were correctly considered in developing the exposure standard; and to examine the uncertainty, variability, and quality of data and the appropriateness of assumptions used in the derivation of the exposure standard. The subcommittee was also asked to identify deficiencies in the MVF database and, where appropriate, to make recommendations for future research and data development.Review of the U.S. Navy's exposure Standard for Manufactured Vitreous Fibers represents the subcommittee's final report. The committee had expanded its review when in January 1999, the Navy revised its Occupational Safety and Health Program Manual (CNO 1999), changing the occupational exposure limit for MVF to the American Conference of Governmental Industrial Hygienists (ACGIH) threshold limit value (TLV) of 1 f/cm3. The report features recommendations by the subcommittee as well as information gaps found throughout investigation. Overall, the subcommittee found that the Navy made a good start in assessing the health effects of MVF, but needed further research.

America is changing. Many of the most noticeable changes in day-to-day life are associated with the advancing capabilities of computer systems, the growing variety of tasks they can accomplish, and the accelerating rate of change. Advanced engineering environments (AEEs) combine advanced, networked computer systems with advanced modeling and simulation technologies. When more fully developed, AEEs will enable teams of researchers, technologists, designers, manufacturers, suppliers, customers, and other users scattered across a continent or the globe to develop new products and carry out new missions with unprecedented effectiveness. Business as usual, however, will not achieve this vision. Government, industry, and academic organizations need to make the organizational and process changes that will enable their staffs to use current and future AEE technologies and systems. Design in the New Millennium: Advanced Engineering Environments: Phase 2 is the second part of a two-part study of advanced engineering environments. The Phase 1 report, issued in 1999, identified steps the federal government, industry, and academia could take in the near term to enhance the development of AEE technologies and systems with broad application in the U.S. engineering enterprise. Design in the New Millennium focuses on the long-term potential of AEE technologies and systems over the next 15 years. This report calls on government, industry, and academia to make major changes to current organizational cultures and practices to achieve a long-term vision that goes far beyond what current capabilities allow.

On June 24-25, 1999, the Committee on Integrating the Science of Early Childhood Development of the Board on Children, Youth, and Families of the National Research Council/National Academy of Sciences and the Institute of Medicine convened a workshop for researchers and practitioners to examine the underlying knowledge base that informs current best practices in early childhood services, from the prenatal period to school entry. Early Childhood Intervention discusses the diversity of working assumptions, theories of change, and views about child development and early intervention that currently shape a wide variety of social policies and service delivery systems for young children and their families.

Network-Centric Naval Forces: A Transition Strategy for Enhancing Operational Capabilities is a study to advise the Department of the Navy regarding its transition strategy to achieve a network-centric naval force through technology application. This report discusses the technical underpinnings needed for a transition to networkcentric forces and capabilities.