Acute Leukemia, An Issue of Hematology/Oncology Clinics of North America

Includes topics such as: CLL - A Historical Perspective; Incidence & Epidemiology; Biology, Molecular Biology & Cytogenetics of CLL; What does the status of smatic hypermutations in IGVH genes tell us about the origin of CLL?; What does the status of ZAP-70 tell us about the biology of CLL? And, approach to initial therapy - When to start therapy?