Using the experience of patients, users, healthcare professionals and other stakeholders to innovate and rethink healthcare organizations and systems is gaining ground. Deploying these innovative methods and practices, however, requires an understanding and mastery of theoretical principles, as well as experimenting with them in the field. Experience in Healthcare Innovation alternates between theoretical presentations and case studies/examples in order to present the key notions of innovation in healthcare and the experiences of the people at the heart of healthcare ecosystems. It brings together diverse and complementary perspectives, shedding new light on the issue of healthcare experience through the prism of innovation. It includes a wealth of resources, ideas and results for all of those in healthcare wishing to implement innovative approaches that place the human experience at the heart of healthcare ecosystems.
Nuclear Physics 2 explores the applications of various radioisotopes for dating and nuclear medicine imaging. It introduces the theoretical and experimental facts from the observation of the red shift in the spectrum of galaxies (1913), and the discovery of the cosmic microwave background (1965) that led to the validation of the Big Bang model, through which all known chemical elements are created via nucleosynthesis processes. This introduction is followed by a description of the nuclear reactions involved in primordial, stellar, and explosive. The principles of carbon-14, potassium-argon, uranium-thorium and uranium-protactinium dating, along with the principles of lead-210, caesium-137 and beryllium-7 radiochronometers applied to dating, are also described. An overview of the birth of nuclear medicine is given, from the first use of radioisotopes as tracers in plant biology in 1913, to the development of Positron Emission Tomography (PET) in 1975. The method of synthesis of radiopharmaceuticals, quality control of radiopharmaceuticals and the experimental methods of the determination of radiochemical purity are presented. The description of the principles of PET and Single-Photon Emission Tomography (SPECT), the presentation of the different radioisotopes used in TEMPS and PET, as well as the presentation of the main scintigraphies and their uses in nuclear medicine conclude the topics studied.
Media coverage of scientific issues is a highly complex process. It involves making a specialized field accessible to the general public, without necessarily disseminating the associated scientific terms or knowledge. The terminological interactions between press discourses and scientific knowledge are presented within the field of agroecology. The analysis of textual data focuses on articles in the general press in French and English, devoted to plant protection practices using natural mechanisms (biological control). This book provides a terminological and cognitive overview of the issues involved in popularizing science in a rapidly expanding field, and of the challenges to be met in the constantly evolving environmental communication sector.
Software testing has greatly evolved since the first edition of this book in 2011. Testers are now required to work in "agile" teams and focus on automating test cases. It has thus been necessary to update this work, in order to provide fundamental knowledge that testers should have to be effective and efficient in today's world. This book describes the fundamental aspects of testing in the different lifecycles, and how to implement and benefit from reviews and static analysis. Multiple other techniques are approached, such as equivalence partitioning, boundary value analysis, use case testing, decision tables and state transitions. This second edition also covers test management, test progress monitoring and incident management, in order to ensure that the testing information is correctly provided to the stakeholders. This book provides detailed course-study material for the 2023 version of the ISTQB Foundation level syllabus, including sample questions to help prepare for exams.
The world is full of traces of the past, ranging from things as different as monuments and factories to farms, eco-museums, landscapes, mountaineering and even woven-grass bridges. These traces must be protected and passed on to future generations. Communicational analysis shows that these traces have acquired the status of heritage by becoming communicative beings imbued with a new social life. Up until the 1970s and 1980s, granting this status was the prerogative of the state. New modes then emerged, increasingly involving social actors and the publicization of knowledge. Today, the heritage recognition of these traces also depends on interpretative schemes that circulate in society, notably through the media. Heritage Traces in the Making is aimed at anyone - researchers, professionals and students - who is interested in how heritage is created and how it evolves.
Enzyme dysfunction, an essential catalyst for the smooth running of biochemical reactions and the maintenance of vital processes, is at the root of many pathologies that have paved the way for the development of numerous drugs. Aimed at pharmacists, biologists, biochemists, doctors, veterinarians, medicinal chemists and students from a wide range of disciplines, Enzymes and Drugs brings together, for the first time, extensive documentation highlighting the relationships between a large number of drugs and enzymes. The book also highlights new prospects for therapeutic discoveries offered by enzyme targeting. Numerous applications have been developed thanks to strategies for studying enzyme inhibition or activation, as well as the development of allosteric effectors, presented with their advantages and disadvantages. Various rare diseases, known as "orphan" diseases, have resulted from enzyme deficiency or absence. For their treatment, the introduction of substitute enzymes has led to major therapeutic advances.
Faced with global economic, social and environmental challenges requiring us to go beyond individual actions, the development of collective dynamics is the ideal response. From this perspective, territories, which have long been neglected, are now asserting themselves as breeding grounds for innovative and relevant forms of organized action in response to shared experiences. Bringing together more than twenty researchers in strategic management, human resources management and marketing, Collective Dynamics and Territories offers, through nine territorial issues (innovating and regenerating territories, building environmental action, attracting and retaining talent, etc.), insights into the conditions and modalities for developing collective dynamics within territories. The success of local collective dynamics depends on support for the actors involved, from situation analysis to problem definition, including idea generation, selection, implementation and evaluation. This book offers a comprehensive, systemic and operational vision for analyzing and acting on collective territorial dynamics.
This book studies the principles of mechanical energy conversion used in renewable energy sources derived from air and water: wind power, tidal power, hydroelectric power, osmotic energy, ocean thermal energy and wave energy. Mechanical Energy Conversion presents twelve application exercises and their answers. They enable the reader to first understand the physical principles of mechanical energy converters and then learn the method for sizing them. The book also reinforces the concepts of fluid mechanics and hydraulic turbo machinery, which are required to solve the exercises. This book aims to instruct readers on how to design an energy system. For each renewable energy source covered - and based on the quantity of energy or power supplied - it describes the production process, explains how it works and calculates the characteristics and dimensions of its components.
With increased competition from new wine-producing countries and substitute products, declining wine consumption, climate change, health crises and geopolitical contexts, the wine industry has been facing serious difficulties in recent years. Paradoxically, however, this recent period also offers new opportunities. Through the presentation of original research results, reading grids, illustrations and case studies, Wine Management and Marketing 2 analyzes the main challenges facing the wine industry and considers new opportunities: a renewed dynamism of technical, organizational and commercial innovations; the adaptability of actors; a greater introduction of new technologies; etc. The multi-faceted approach adopted by the authors and experts offers an enriched reflection, which provides a better understanding of the current state of the wine industry, and presents various levers for adapting to new commercial, societal and environmental expectations.
The theory of dynamic systems is addressed in this book in accordance with the "modern" approach, heir to algebraic analysis, which has been implemented since the last decade of the 20th century. After a reminder of the evolution of the representation of systems based on transfer functions or matrices, the duality of controllability and observability is revisited, and new results are produced concerning time-varying discrete-time systems. To complete and improve the existing analyses, the poles and zeros of linear systems and their interconnections are presented in a new way, as well as the problem of systems governed by functional differential equations (of retarded or neutral type) and their stabilization. This book also proposes known and original mathematical complements.
Students' difficulties in producing texts that meet the requirements of academic writing are a recurring concern for teaching staff and those responsible for university courses. Various initiatives are currently being taken, mainly at undergraduate level, to help students improve the quality of their writing. Research into metacognitive processes and the self-regulation of learning can be used to support the design of these writing support systems, particularly by providing a better understanding of the students' difficulties. This book reviews the concepts of metacognition and self-regulation in relation to writing processes. It analyses the metacognitive components involved in text production, their links with successful writing and their individual and contextual determinants. It completes this analysis by drawing on the teaching and assessment of writing in higher education. All of these elements are articulated around a multifactorial modeling of the learning and teaching of academic writing.
Subtractive sound synthesis is one of the most widely used techniques in electronic music and in many analog synthesizers since the early 1960s. It is based on a simple principle, but its operation is complex, involving many parameters. It can be enhanced by a variety of effects that give the sound its authenticity, and does not simply imitate musical instruments, but can also transcribe noises present in natural soundscapes or generate entirely synthetic sounds. Synthesizers and Subtractive Sound Synthesis 2 presents practical exercises, ranging from the fundamentals to advanced functionalities. Most of the sound effects applicable to subtractive synthesis are covered: vibrato, phaser, reverb, etc. The final chapters deal with polyphony and arpeggiator-sequences.
Silicon is the material of the digital revolution, of solar energy and of digital photography, which has revolutionized both astronomy and medical imaging. It is also the material of microelectromechanical systems (MEMS), indispensable components of smart objects. The discovery of the electronic and optoelectronic properties of germanium and silicon during the Second World War, followed by the invention of the transistor, ushered in the digital age. Although the first transistors were made from germanium, silicon eventually became the preferred material for these technologies. Silicon, From Sand to Chips 1 traces the history of the discoveries, inventions and developments in basic components and chips that these two materials enabled one after the other. The book is divided into two volumes and this first volume is devoted to basic microelectronic components.
Silicon is the material of the digital revolution, of solar energy and of digital photography, which has revolutionized both astronomy and medical imaging. It is also the material of microelectromechanical systems (MEMS), indispensable components of smart objects. The discovery of the electronic and optoelectronic properties of germanium and silicon during the Second World War, followed by the invention of the transistor, ushered in the digital age. Although the first transistors were made from germanium, silicon eventually became the preferred material for these technologies. Silicon, From Sand to Chips 2 traces the history of the discoveries, inventions and developments in basic components and chips that these two materials enabled one after the other. The book is divided into two volumes and this second volume is devoted to microelectronic and optoelectronic chips, solar cells and MEMS.
Contact in Structural Mechanics treats the problem of contact in the context of large deformations and the Coulomb friction law. The proposed formulation is based on a weak form that generalizes the classical principle of virtual powers in the sense that the weak form also encompasses all the contact laws. This formulation is thus a weighted residue method and has the advantage of being amenable to a standard finite element discretization. This book provides the reader with a detailed description of contact kinematics and the variation calculus of kinematic quantities, two essential subjects for any contact study. The numerical resolution is carried out in statics and dynamics. In both cases, the derivation of the contact tangent matrix - an essential ingredient for iterative calculation - is explained in detail. Several numerical examples are presented to illustrate the efficiency of the method.
Awareness of complexity in science and technology dates back to the 1970s. However, all social systems tend to develop structures that become more complex over time, be it within families, tribes, cities, states, or societal and economic organizations. Complexities 2 covers a broad array of fields, from justice and linguistics to education and organizational management. The aim of this book is to show, without aiming to provide a comprehensive overview, the diversity of approaches and behaviors towards the obstacle of complexity in understanding and achieving human actions. When we see complexity as the incompleteness of knowledge and the uncertainty of the future, we realize that simplifying is not an adequate approach to complexity, even in the humanities and social sciences. This book explores the relationship between order and disorder in this field of knowledge.
Artificial and Cognitive Computing for Sustainable Healthcare Systems in Smart Cities delves into the transformative potential of artificial and cognitive computing in the realm of healthcare systems, maintaining a specific emphasis on sustainability. By exploring the integration of advanced technologies in smart cities, the authors examine and discuss how AI and cognitive computing can be harnessed to enhance healthcare delivery. The book provides focused navigation through innovative solutions and strategies that contribute to the creation of sustainable healthcare ecosystems within the dynamic environment of smart cities. From optimizing resource utilization to improving patient outcomes, this comprehensive exploration provides insight for readers with an interest in the future of healthcare within the era of intelligent urban development.
The use of digital technology in our societies is growing to meet the ever-increasing challenges of data collection, raising awareness, education and understanding nature. Artificial intelligence, for example, appears to be the answer to collecting massive amounts of data on biodiversity at a global scale and facilitating citizen participation in such data collection. Linking with Nature in the Digital Age explores the reconfiguration of our relationship with nature within this digital framework. This book examines this mediated linking from three angles. Firstly, it shows how digital technology can foster the development of links to nature. Then, it describes in greater detail the materiality of these links and how they have evolved with the developments in information technology. Finally, it questions the belief in the digital as a facilitator and opens up new perspectives on our relationship with nature and the living world
Behind the neologism "ribozymes" lies a family of fascinating molecules, ribo-enzymes, which have been relatively little studied. These catalytically active RNAs are found in all strata of life, from viruses to the human genome. At the end of the 1970s, the discovery of a catalytic RNA nestled in an intron, followed by another involved in the maturation of transfer RNAs, led to the discovery of new ribozymes and the transition from a strictly "proteocentric" vision, inherited from the dogma of molecular biology, to a more "nucleocentric" one. Since then, a variety of ribozymes have been identified in genomes, where their functions often remain mysterious. Looking at Ribozymes traces the discovery of these molecules and presents a picture of their functional diversity, catalytic mechanisms and distribution within the tree of life.
This book is devoted to the construction and study of approximate methods for solving mathematical physics problems in canonical domains. It focuses on obtaining weighted a priori estimates of the accuracy of these methods while also considering the influence of boundary and initial conditions. This influence is quantified by means of suitable weight functions that characterize the distance of an inner point to the boundary of the domain. New results are presented on boundary and initial effects for the finite difference method for elliptic and parabolic equations, mesh schemes for equations with fractional derivatives, and the Cayley transform method for abstract differential equations in Hilbert and Banach spaces. Due to their universality and convenient implementation, the algorithms discussed throughout can be used to solve a wide range of actual problems in science and technology. The book is intended for scientists, university teachers, and graduate and postgraduate students who specialize in the field of numerical analysis.
This book presents a biography of the Danish botanist Eugen Warming. As the author of a treatise on ecology that brought him international recognition, he was able to inspire the first generation of 20th-century European and American ecologists. His innovative approach to nature and his Arctic and tropical missions heralded the birth of a new science and an ecological awareness. As a professor at several Scandinavian universities during a period of intense debate and controversy over evolutionary theories, Eugen Warming vigorously asserted his convictions. Birth of Scientific Ecology presents the image of a man of knowledge and power, recognized by his contemporaries as a founder of ecology and a player in the ecological project of the Kingdom of Denmark at a time when the empires were clashing.
Subtractive sound synthesis has been one of the most widely used techniques in electronic music and for many analog synthesizers since the early 1960s. It is based on a simple principle, but its operation remains complex, involving many parameters. It can be enriched by a variety of effects that give the sound its authenticity. It does not just imitate musical instruments, but can also transcribe noises present in natural soundscapes, or generate entirely synthetic sounds. Synthesizers and Subtractive Synthesis 1 presents the theoretical basis of a sound phenomenon, the different types of synthesis, the components that are required and present in synthesizers, the working environment specific to the study of subtractive synthesis, and the hardware and software available. After reading the various chapters of this book, readers will have a clear vision of the tools and actions required to grasp the world of subtractive sound.
At the end of the Second World War, a new technological trend was born: integrated electronics. This trend relied on the enormous rise of integrable electronic devices. Analog Devices and Circuits is composed of two volumes: the first deals with analog components, and the second with associated analog circuits. The goal here is not to create an overly comprehensive analysis, but rather to break it down into smaller sections, thus highlighting the complexity and breadth of the field. This first volume, after a brief history, describes the two main devices, namely bipolar transistors and MOS, with particular importance given to the modeling aspect. In doing so, we deal with new devices dedicated to radio frequency, which touches on nanoelectronics. We will also address some of the notions related to quantum mechanics. Finally, Monte Carlo methods, by essence statistics, will be introduced, which have become more and more important since the middle of the twentieth century. The second volume deals with the circuits that "use" the analog components that were introduced in Volume 1. Here, a particular emphasis is placed on the main circuit: the operational amplifier.
Since 1971, UNESCO's Man and the Biosphere (MAB) Programme has embraced a number of principles that link the political, scientific and academic spheres. Biosphere Reserves and Sustainable Development Goals 2 is a reminder of the fundamental issues involved in governance. The diversity and multiplicity of stakeholders, and the complexity of the interplay between them, as well as their organization, are decisive factors in the proper management of resources and territories. The book also presents a number of case studies demonstrating that, between the strong development aspirations of their populations, the impact of human activities and the need to conserve their biological heritage, the biosphere reserves of the southern Mediterranean are facing major issues: agricultural pollution, forest fires, water use in a context of climate change, etc.
Inventing isn't easy! In this book, twelve "valleys of death" are identified which, following a linear approach, correspond to the various obstacles that limit the various passages from an original idea to invention, and then to industrial innovation. These various limiting factors have a variety of origins: disciplined scientific training, weak general and scientific culture, New Public Management, hierarchical support, funding, evaluation, proof of concepts, complexity management, and heuristic and interdisciplinary approaches on the one hand, and attractiveness for the new on the other. After an idea is formulated, these contexts bring small elements of science into play, but above all human aspects ranging from motivation and the quality of exchanges to responsibility. In short, it is a possible dynamic way of living together to promote innovations stemming from science. This is not easy, but if the invention is profitable for society, the downstream sector can greatly facilitate the various stages of commercialization.
Numerical modeling now plays a central role in the design and study of electromagnetic systems. In the field of devices operating in low frequency, it is the finite element method that has come to the fore in recent decades. Today, it is widely used by engineers and researchers in industry, as well as in research centers. This book describes in detail all the steps required to discretize Maxwell's equations using the finite element method. This involves progressing from the basic equations in the continuous domain to equations in the discrete domain that are solved by a computer. This approach is carried out with a constant focus on maintaining a link between physics, i.e. the properties of electromagnetic fields, and numerical analysis. Numerous academic examples, which are used throughout the various stages of model construction, help to clarify the developments.
Successive IPCC reports consistently stress the devastating impact of human activity on the climate. An ecological transition seems essential to modify our economic and social system, while meeting the needs of current and future generations. As the main culprits of environmental destruction, companies must modify their production methods to reduce their negative impact on the environment. Eco Design and Ecological Transition presents an innovative approach to eco design, a method that aims to offer products or services with a reduced environmental impact compared to conventional production methods, from the extraction of resources to the end of the product's life. The book also analyzes the potential of the circular economy and frugal innovation. It shows that innovation, to be sustainable, must be both environmentally and socially sustainable. From a systemic point of view, it examines the ability of players, particularly companies, to change their strategies in order to combine human well-being and respect for the environment in the context of ecological transition.
Since 1971, UNESCO's Man and the Biosphere (MAB) Programme has embraced a number of principles that link the political, scientific and academic spheres. Biosphere Reserves and Sustainable Development Goals 1 presents these areas as privileged spaces for experimenting with operating methods specific to cross-cutting objectives and issues. These areas encourage the development of interdisciplinary research, supported by a worldwide network to disseminate experience, approaches and knowhow. The various global and local political scales are linked here, with different consequences for the reconfiguration of local political arenas, for specific modes of development linked to a renewed relationship with knowledge, powers and institutions, and for renewed relationships between the worlds of science, education and territorial governance.
Cultural heritage is increasingly recognized for its contributions to the transition to climate action, and heritage education can play an important role in developing climate adaptation competencies. These can foster positive dialogs surrounding climate change, shift attitudes and inspire actions. However, achieving these goals requires bridging the gap between policy, practice and local capacity building, as well as integrating a multi- and transdisciplinary approach into traditional higher education curricula and models. Bringing together knowledge, practice and experiences from different disciplinary silos, this book provides a wide set of innovative teaching and learning methods, tools and pedagogical models that can be adapted to heritage education in order to address climate issues. Organized into four parts, Heritage Education for Climate Action covers a wide array of international experiences, real-life cases and practices, focusing on heritage and resilience building, vulnerability and risk assessment, climate change adaptation, mitigation and policymaking. This book is therefore a source of suggestions and ideas for scholars, educators and professionals who want to develop future climate leadership and contribute to the transition of heritage education toward sustainable development and climate action.
Today's information technology, along with Artificial Intelligence (AI), is moving towards total communication between all computerized systems. AI is a representation of human intelligence based on the creation and application of algorithms in specific computer environments. Its aim is to enable computers to act like human beings. For it to work, this type of technology requires computer systems, data with management systems and advanced algorithms, used by AI. In mechanical engineering, AI can offer many possibilities: in mechanical construction, predictive maintenance, plant monitoring, robotics, additive manufacturing, materials, vibration control and agro composites, among many others. This book is dedicated to Artificial Intelligence uncertainties in mechanical problems. Each chapter clearly sets out used and developed illustrative examples. Aimed at students, Uncertainty and Artificial Intelligence is also a valuable resource for practicing engineers and research lecturers.
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