Antibacterial Activity Study of Polyester Amides

The main aim of this research is to synthesize a new class of
multifunctional poly(ester amides) (PEAs), characterize them and to study their
structure-property relationship. These PEAs were synthesized by direct
polycondensation of 2,5-pyridine dicarboxylic acid with various diols and three other
varying diamines using diphenylphosphoryl chloride (DPPC) as the condensation
agent in pyridine solution. In order to study the effect of the thermal stability and
optical property, monomers of different molecular structures were used. The present
investigation also focuses on the study of anti-bacterial, anti-cancer activities and
wound healing capacity of the synthesized PEAs. Moreover nanofibers formed by
using electrospinning technique with blends of PEAs in PVC matrix were studied for
assessing the applicability of PEAs as nanofibers. This chapter highlights literature on
the role of various synthetic PEAs which result from the several combinations of
monomers in order to design materials with desirable properties for several
applications in various fields.