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Om Formulating Poorly Water Soluble Drugs

The objective of this third edition is to consolidate within a single text the most current knowledge, practical methods, and regulatory considerations pertaining to formulations development with poorly water-soluble molecules. A pharmaceutical scientist¿s approach toward solubility enhancement of a poorly water-soluble molecule typically includes detailed characterization of the compound¿s physiochemical properties, solid-state modifications, advanced formulation design, non-conventional process technologies, advanced analytical characterization, and specialized product performance analysis techniques. The scientist must also be aware of the unique regulatory considerations pertaining to the non-conventional approaches often utilized for poorly water-soluble drugs. One faced with the challenge of developing a drug product from a poorly soluble compound must possess at a minimum a working knowledge of each of the above mentioned facetsand detailed knowledge of most. In light of the magnitude of the growing solubility problem to drug development, this is a significant burden especially when considering that knowledge in most of these areas is relatively new and continues to develop.

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  • Språk:
  • Engelska
  • ISBN:
  • 9783030887186
  • Format:
  • Inbunden
  • Sidor:
  • 708
  • Utgiven:
  • 20. maj 2022
  • Utgåva:
  • 22003
  • Mått:
  • 183x44x260 mm.
  • Vikt:
  • 1506 g.
Leveranstid: 2-4 veckor
Förväntad leverans: 18. december 2024

Beskrivning av Formulating Poorly Water Soluble Drugs

The objective of this third edition is to consolidate within a single text the most current knowledge, practical methods, and regulatory considerations pertaining to formulations development with poorly water-soluble molecules. A pharmaceutical scientist¿s approach toward solubility enhancement of a poorly water-soluble molecule typically includes detailed characterization of the compound¿s physiochemical properties, solid-state modifications, advanced formulation design, non-conventional process technologies, advanced analytical characterization, and specialized product performance analysis techniques. The scientist must also be aware of the unique regulatory considerations pertaining to the non-conventional approaches often utilized for poorly water-soluble drugs. One faced with the challenge of developing a drug product from a poorly soluble compound must possess at a minimum a working knowledge of each of the above mentioned facetsand detailed knowledge of most. In light of the magnitude of the growing solubility problem to drug development, this is a significant burden especially when considering that knowledge in most of these areas is relatively new and continues to develop.

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